Evidence map›Paper›PMID 39995641›Full record

ArticleReports of biochemistry & molecular biology2024

Mec-A Positive Methicillin-Susceptible

Sri Amelia, Rozaimah Zain-Hamid, Lia Kusumawati, Zulham Yamamoto, Dewi Santosaningsih, Putri Chairani Eyanoer, Sunna Vyatra Hutagalung, Masrul Lubis, Alvin Ivander

Abstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. PeerJ · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sri AmeliaDepartment of Microbiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Rozaimah Zain-HamidDepartment of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Lia KusumawatiDepartment of Microbiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Zulham YamamotoDepartment of Histology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Dewi SantosaningsihDepartment of Microbiology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Putri Chairani EyanoerDepartment of Community and Preventive Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Sunna Vyatra HutagalungDepartment of Parasitology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Masrul LubisDivision of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Alvin IvanderFaculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Clinical infection samples obtained from blood were collected and categorised as MRSA or Methicillin-sensitive Staphylococcus aureus (MSSA) using the VITEK-2 compact device. Subsequently, specific samples were gathered as case series owing to their unique characteristics. Resistance genes were detected using conventional polymerase chain reaction (PCR), followed by visualisation through electrophoresis. Results: Our findings were based on the identification of five instances of MSSA among samples obtained from a tertiary hospital's microbiology laboratory. Using the VITEK-2 antimicrobial susceptibility profile, these cases were determined to be MSSA. Subsequently, we conducted PCR, which revealed the presence of a mec-a-positive strain. Upon re-examination using Mueller-Hinton agar, the five strains were confirmed to be MSSA. Further analysis demonstrated that all strains were positive for Panton-Valentine leucocidin Conclusions: The positive mec-A MSSA results should serve as a warning to clinicians that a resistant strain is forthcoming. mec-A continues to be the benchmark for confirming the resistance phenotype. Additional research is essential to explore this strain.

Indexed as

mec-aMSSAStaphylococcus aureus

Identifiers

PMID39995641
PMCPMC11847588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.