ReviewBiochemistry and biophysics reports2025
Apoptosis-inducing proteins with reduced expression in breast cancer: A review article.
Review in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Antineoplastic effect of anastrozole-loaded polymer nanocapsules on malignant human breast cancer cells (MCF-7).Scientific reports · 2025Article
- Thiazole derivatives in cancer therapy: mechanistic insights, bioactivity, and future perspective.Future medicinal chemistry · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is considered one of the most abundant malignancies with high morbidity and mortality. Traditional cancer treatments possess various weaknesses, including a lack of specificity and numerous side effects. Novel cancer therapies aim to overcome the shortcomings of traditional therapies and offer more efficient and safe treatments. Designing and identifying novel proteins that can practically and specifically inhibit tumors by inducing apoptosis can interest researchers in this field. This review discusses recent studies on the use of four promising proteins, KAI1, Apoptin, BIF-1, and DFF-40, for breast cancer treatment. This study also focuses on alterations in the expression of the androgenic proteins and novel strategies for better penetration and delivery of these proteins. Lastly, prospects for protein-based targeted cancer therapy and future studies in this field are highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.