ArticlePsychological medicine2025
Family functioning in families with 11-year-old children at familial high risk of schizophrenia or bipolar disorder and population-based controls: The Danish High Risk and Resilience Study VIA 11.
Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Article
- Study protocol for the Danish High Risk and Resilience Study VIA 19 - from age 15 to age 19: transition from adolescence to early adulthood.Frontiers in psychiatry · 2026Article
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Authors and funding
13 authors.
Funding
Abstract
backgroundPoorer family functioning during childhood is associated with severe mental disorders in adulthood in the general population. However, family functioning is understudied in families with parental schizophrenia or bipolar disorder. We aimed to investigate family functioning in families with 11-year-old children of parents with schizophrenia or bipolar disorder compared with controls. Second, we aimed to examine associations between family functioning and levels of child psychopathology, child global functioning, and parental social functioning.
methodsIn this prospective, population-based cohort study, we included 160 families with parental schizophrenia, 95 families with parental bipolar disorder, and 177 control families. Family functioning was measured with the 12-item version of the McMaster Family Assessment Device - General Functional Scale.
resultsFamilies with parental schizophrenia (Cohen's
conclusionsChildren in families with parental schizophrenia or bipolar disorder are at increased risk of experiencing family dysfunction, and poorer family functioning confers risk for more symptoms of child psychopathology and poorer parental social functioning. Future studies should investigate the potentially predictive value of family dysfunction in relation to later illness onset and other adverse outcomes in these populations.
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