Evidence map›Paper›PMID 39994901›Full record

ArticleHead & neck2025

Advanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey.

Grant Creaney, Mariél de Aquino Goulart, Alex McMahon, Claire Paterson, James McCaul, Sandra Perdomo, Laura Mendoza, Laia Alemany, Lidia Maria Rebolho Arantes, Paula Andrea Rodriguez Urrego and 24 more

Abstract read
In one paragraph

Article in Head & neck, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Grant CreaneySchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.ORCID 0000-0001-9972-7629
Mariél de Aquino GoulartSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.ORCID 0000-0001-5263-6746
Alex McMahonSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Claire PatersonGlasgow Head and Neck Cancer (GLAHNC) Research Group, Glasgow, UK.ORCID 0000-0002-1691-5016
James McCaulQueen Elizabeth University Hospital, Glasgow, UK.
Sandra PerdomoInternational Agency for Research on Cancer (IARC), Lyon, France.
Laura MendozaUniversidad Nacional de Asunción, Asuncion, Paraguay.
Laia AlemanyInstitut Catala D'oncologia, Barcelona, Spain.
Lidia Maria Rebolho ArantesHospital de Câncer de Barretos, Barretos, Brazil.ORCID 0000-0001-8230-1218
Paula Andrea Rodriguez UrregoDepartment of Pathology and Laboratories, Fundacion Santa Fe de Bogota, Bogota, Colombia.
Tom DuddingBristol Dental School, University of Bristol, Bristol, UK.
Mirana PringBristol Dental School, University of Bristol, Bristol, UK.
Marta VilenskyUniversidad De Buenos Aires, Buenos Aires, Argentina.
Cecilia CuffiniVirology Institute, School of Medicine.Universidad Nacional de Córdoba, Córdoba, Argentina.
Silvia Adriana Lopez de BlancFacultad de Odontología, Universidad Nacional de Córdoba, Cordoba, Argentina.
José Carlos de OliveiraAraujo Jorge Hospital Brasil Goiânia Cancer Registry, Goiania, Brazil.
Shahid PervezAga Khan University, Karachi, Pakistan.
Pierre SaintignyCentre Leon Berard, Lyon, France.
Mauricio CuelloService of Oncology, Manuel Quintela Hospital, Montevideo, Uruguay.
Jaroslav BetkaDepartment of Otorhinolaryngology and Head and Neck Surgery, 1st. Faculty of Medicine, Charles University in Prague, Faculty Hospital Motol, Prague, Czechia.
Luis Felipe Ribeiro PintoBrazilian Ministry of Health/Instituto National De Cancer, Rio De Janeiro, Brazil.
Maria Paula CuradoA. C. Camargo Centre, Sao Paulo, Brazil.ORCID 0000-0001-8172-2483
Kazem ZendehdelTehran University of Medical Sciences, Tehran, Iran.
Lorenzo RichiardiCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, and CPO-Piemonte, Turin, Italy.
Maja PopovicCancer Epidemiology Unit, Department of Medical Sciences, University of Turin, and CPO-Piemonte, Turin, Italy.ORCID 0000-0003-4500-6572
José Roberto de PodestaServiço de Cirurgia de Cabeça e Pescoço, Associação Feminina de Educação e Combate ao Câncer, Vitória, Brazil.
Sandra Ventorin von ZeidlerPathology Department, Federal University of Espírito Santo, Vitória, Brazil.
Ricardo Mai RochaServiço de Cirurgia de Cabeça e Pescoço, Associação Feminina de Educação e Combate ao Câncer, Vitória, Brazil.
HEADSpAcE ConsortiumInternational Agency for Research on Cancer (IARC), Lyon, France.
Shaymaa AlwaheidiInternational Agency for Research on Cancer (IARC), Lyon, France.
Paul BrennanInternational Agency for Research on Cancer (IARC), Lyon, France.
Shama ViraniInternational Agency for Research on Cancer (IARC), Lyon, France.
Al RossSchool of Health, Education, Policing and Sciences, Staffordshire University, Stafford, UK.
David I ConwaySchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.ORCID 0000-0001-7762-4063

Funding

European Union's Horizon 2020 Framework Programme 825771World Health Organization 001
6 · The paper itself

Abstract

backgroundGlobally, most people with head and neck cancers (HNCs) are diagnosed with advanced-stage disease. HNC diagnostic stage has multifactorial explanations, with the role of health system factors not yet fully investigated.

methodsHNC centres (n = 18) from the HEADSpAcE Consortium were surveyed via a bespoke health system questionnaire covering a range of factors. Centres were compared using the least square means for the presence/absence of each health system factor to their proportion of advanced-stage HNC.

resultsHealth system factors associated with lower proportion in advanced-stage diagnosis were formal referral triaging (14%, 95% CI-0.26, -0.03), routine monitoring of time from referral to diagnosis (16%, 95% CI-0.27, -0.05), and fully publicly funded systems (17%, 95% CI-0.29, -0.06). Several health systems factors had no routinely available data.

conclusionsThrough identifying and monitoring health systems factors associated with lower proportions of advanced stage HNC, interventions could be developed, and systems redesigned, to improve early diagnosis.

Indexed as

BenchmarkingHead and Neck NeoplasmsEarly Detection of CancerFemaleHumansMaleNeoplasm StagingReferral and ConsultationSurveys and QuestionnairesTriagediagnostic pathwayhead and neck cancerhealth systemsstage at diagnosis

Identifiers

PMID39994901
PMCPMC12146806

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.