ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging
Blood Flow Velocities as Determined by Real-Time Phase-Contrast MRI in Patients With Carotid Artery Stenosis.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Real-time phase-contrast MRI can be used to quantify cerebrovascular reserve capacity - a comparative study to neurovascular ultrasound in healthy subjects.Neuroimage. Reports · 2026Article
- Transcranial Doppler ultrasound validation of BOLD-fMRI cerebral blood flow relationship.Magnetic resonance in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeReal-time phase-contrast (RT-PC) flow MRI can be used to determine quantitative flow parameters throughout the vessel lumen of extracranial, brain-supplying arteries. Its potential value in the diagnostic workup of patients with carotid artery stenosis has not been evaluated.
methodsRT-PC flow MRI was performed in 10 patients with carotid stenosis in comparison to conventional neurovascular ultrasound (nvUS). Peak systolic velocity, end-diastolic velocity, mean flow velocity, and flow volumes have been evaluated by RT-PC flow MRI. Measurements have been performed at standardized sites along the common, internal, and external carotid arteries on both sides and at the maximum of the carotid stenosis.
resultsBlood flow velocities were significantly lower with RT-PC flow MRI compared to nvUS and not consistently correlated between both methods. Within the maximum of the carotid stenosis, RT-PC flow MRI showed implausible flow velocity reductions compared to nvUS. In contrast, the flow volumes determined by RT-PC flow MRI-with exception of the stenosis maximum-were comparable with nvUS and significantly correlated in the prestenotic common carotid artery.
conclusionRT-PC flow MRI does not appear to be suitable for quantifying blood flow velocities and volumes in the patients with carotid stenosis compared to nvUS. Apart from the lower temporal resolution of RT-PC MRI, the lack of correlation of blood flow velocities might be ascribed to the prevalence of nonlaminar flow within and behind the stenosis, which violates a general prerequisite for valid flow velocity measurements by PC MRI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.