Evidence map›Paper›PMID 39994770›Full record

ArticleReproductive health2025

Association analysis of maternal exposure to air pollution during pregnancy and offspring asthma incidence.

Lili Bao, Yuan Liu, Yuhong Zhang, Qian Qian, Yifen Wang, Wei Li, Yanyan Yu

Abstract read
In one paragraph

Article in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Immune development in early life.Nature immunology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lili Bao *Department of Pediatrics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215006, China.
Yuan Liu *Children Asthma Department, Lianyungang Maternal and Child Health Hospital, Lianyungang, 222006, China.
Yuhong Zhang *Children Asthma Department, Lianyungang Maternal and Child Health Hospital, Lianyungang, 222006, China.
Qian QianChildren Asthma Department, Lianyungang Maternal and Child Health Hospital, Lianyungang, 222006, China.
Yifen WangChildren Asthma Department, Lianyungang Maternal and Child Health Hospital, Lianyungang, 222006, China.
Wei LiChildren Asthma Department, Lianyungang Maternal and Child Health Hospital, Lianyungang, 222006, China.
Yanyan YuDepartment of Pediatrics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215006, China. szslyyek@126.com.

Funding

General Projects of Social Development in Jiangsu Province BE2019694
6 · The paper itself

Abstract

backgroundAir pollution has a significant negative impact on human health. Pregnant mothers and children are typical susceptible groups, and environmental exposure has a crucial impact on children's health. We established a childhood asthma cohort to analyze the factors influencing the development of asthma in offspring, with a focus on prenatal exposure to air pollutants. The goal was to explore potential early preventive measures to reduce the incidence of childhood asthma.

methodsThis nested case-control study included mothers who were registered and delivered at Lianyungang Maternal and Child Health Hospital between 2015 and 2018, covering pre-pregnancy, first, second, and third trimesters. Children diagnosed with asthma before the age of four were included in the asthma group. To assess environmental exposure, we gathered data from 29 national and provincial air pollution monitoring stations and 16 meteorological monitoring sites in Lianyungang and surrounding areas. We used spatial interpolation with inverse distance weighting (IDW) to estimate individual exposure to air pollutants, including particulate matter (PM

resultsA total of 292 mother-child pairs in the asthma group and 1423 mother-child pairs in the healthy control group were included. The second (AOR = 1.04, 95%CI 1.01-1.06) and whole gestation (AOR = 1.06, 95%CI 1.03-1.10) exposure to PM

conclusionsExposure to PM

Indexed as

Air PollutantsAir PollutionAsthmaMaternal ExposurePrenatal Exposure Delayed EffectsAdultCase-Control StudiesChild, PreschoolChinaFemaleHumansIncidenceInfantInfant, NewbornMaleParticulate MatterAir PollutantsParticulate MatterAir pollutantChildhood asthmaCohortPregnancy

Identifiers

PMID39994770
PMCPMC11849349

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.