Evidence map›Paper›PMID 39994663›Full record

ArticleBMC pediatrics2025

Understanding neonatal unit interventions and breastfeeding outcomes in two hospitals in Ghana to facilitate optimization of newborn care.

Kwabena Onwona-Agyeman, Alhassan Abdul-Mumin, Ganga Lakshmi Srinivas, Edwin Atitsogbui, Jampim Bismark Abrokwah, Asantewaa Gabriella Kyei-Manu, Mohammed Hafiz Kanamu, Mary Joan Kpiniong, Indira Narayanan

Abstract readMulticenter Study
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kwabena Onwona-AgyemanDepartment of Pediatrics, Greater Accra Regional Hospital, Accra, Ghana.ORCID 0009-0008-8997-9855
Alhassan Abdul-MuminUniversity for Development Studies School of Medicine/Tamale Teaching Hospital, Hospital Road, Tamale, NR, Ghana.ORCID 0000-0003-3792-5384
Ganga Lakshmi SrinivasDepartment of Pediatrics, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, 44106Cleveland, OH, Cleveland, United States.ORCID 0000-0003-0760-685X
Edwin AtitsogbuiUniversity of Glasgow, University Avenue, Glasgow, G12 8QQ, United Kingdom.ORCID 0000-0001-7668-2317
Jampim Bismark AbrokwahDepartment of Pediatrics, Greater Accra Regional Hospital, Accra, Ghana.ORCID 0000-0002-8477-8623
Asantewaa Gabriella Kyei-ManuDepartment of Pediatrics, Greater Accra Regional Hospital, Accra, Ghana.ORCID 0009-0009-2090-0595
Mohammed Hafiz KanamuTamale Teaching Hospital, Hospital Road, Tamale, NR, Ghana.ORCID 0009-0006-2873-3769
Mary Joan KpiniongTamale Teaching Hospital, Hospital Road, Tamale, NR, Ghana.ORCID 0009-0007-3701-1482
Indira NarayananGeorgetown University Medical Cente, Washington D.C., United States. inarayanan6@gmail.com.ORCID 0000-0001-8949-9132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInborn babies in many Ghana facilities who need any monitoring or therapy above Essential Newborn Care (ENC) are often separated from postnatal ward dyadic care and sent to Neonatal Units (NUs) due to personnel workload, training gaps or both.

objectivesDescribe (1) care of inborn newborns in NUs at 2 hospitals in Ghana and (2) outcomes, including breastfeeding. We identified stable babies who could potentially be managed by midwives in postnatal wards with appropriate additional training and staffing.

methodsWe conducted a retrospective study from January to December 2022 on inborn newborns in NUs at Greater Accra Regional Hospital (GARH) and Tamale Teaching Hospital (TTH), and the Special Baby Ward at TTH. Data collected included monitoring (glucose), interventions (phototherapy, intravenous antibiotics, thermal and fluid support, oxygen, tube feeds, transfusions) and outcomes (breastfeeding, length of stay, mortality). We used a two-proportion z-test and t-test to test the difference between two proportions and means respectively, with alpha-error of 5% and beta-error 20%. Breastfeeding outcomes were compared between GARH and TTH NUs, and also between babies admitted to the NUs but received no NU interventions and those admitted to the TTH SBW.

resultsOf 2978 inborn newborns admitted to NUs, 11.5% received no NU Interventions. (GARH NU 6.2% (n = 1995) vs. TTH NU 22.1%, (n = 983) p < 0.001). In TTH NU, 3.3% received no listed interventions at all. TTH NU, which administered iv fluids instead of formula to babies during separation, had significantly higher exclusive breastfeeding at discharge. (TTH NU 91.1% vs. GARH NU 66.3%, p < 0.001) Breastfeeding rates were also higher in infants in the TTH SBW vs. infants who received no NU interventions in the TTH NU (TTH SBW 99.3% (n = 261) vs. TTH NU No Intervention group 96.3% (n = 217), p < 0.05).

conclusionsOverall, 11.5% of babies admitted to the two neonatal units did not receive any intensive interventions, including 4.8% of infants < 1800 g. Designing dyadic Intermediate Care between Essential Newborn Care and Special/Intensive care could result in lower census in NUs to permit greater focus on preterm, low-birthweight and sick newborns with higher acuity, and also reduce separation and promote breastfeeding.

Indexed as

Breast FeedingInfant CareIntensive Care Units, NeonatalFemaleGhanaHumansInfant, NewbornLength of StayMaleRetrospective StudiesIntermediate neonatal careLevels of neonatal careLow birthweight babiesPreterm babiesResource utilizationSmall and sick newborns

Identifiers

PMID39994663
PMCPMC11849377

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.