Evidence map›Paper›PMID 39994648›Full record

ArticleBMC oral health2025

Analysis of pain prognosis, medication efficacy, treatment willingness and influencing factors in patients with burning mouth syndrome: a cross-sectional survey.

Qi Zhang, Zhongke Tan, Qianqian Ma, Jiaao Guo, Yanjie Yang

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi Zhang *Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhongke Tan *National Engineering Laboratory for Internet Medical Systems and Applications, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qianqian MaNational Engineering Laboratory for Internet Medical Systems and Applications, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. qian_ma91green@163.com.
Jiaao GuoDepartment of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanjie YangDepartment of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

Henan Provincial Science and Technology Research Project 252102310103Joint Construction Project of Henan Medical Science and Technology Research Plan LHGJ20240254Key Scientific Research Project of Henan Higher Education Institutions 25A330007
6 · The paper itself

Abstract

objectiveTo explore the pain prognosis, medication efficacy and treatment willingness of patients with burning mouth syndrome (BMS) and to identify the factors influencing the pain prognosis, medication efficacy and treatment willingness of patients with BMS.

methodsMedical records of patients who were clinically diagnosed with BMS and who complained of oral mucosal pain at the Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, were retrospectively collected from January 2019 to April 2022. Telephone follow-ups were conducted in August 2024 to investigate the patients' pain prognosis, medication efficacy, willingness for treatment and related treatment information.

resultsAmong the 192 patients, only 31.77% (61/192) reported complete elimination of pain; 37.50% (72/192) reported that the pain still existed but had improved, and 30.73% (59/192) reported no improvement at all. A total of 31.25% (60/192), 34.90% (67/192), and 32.81% (63/192) of the BMS patients evaluated medication efficacy as significantly effective, effective, or ineffective, respectively. Among the 131 patients who still had pain symptoms, 38.17% (50/131) intended to continue treatment. Logistic regression revealed that patients who were older (P = 0.023), who had visited multiple hospitals for treatment (P = 0.001), who were afraid of cancer (P = 0.011) and who were prone to anxiety or depression (P < 0.001) had poorer pain improvement. Patients who had visited multiple hospitals (P < 0.001) and those who were prone to anxiety or depression (P < 0.001) had significantly lower evaluations of medication efficacy. Males (P = 0.041) and those who had visited multiple hospitals (P < 0.001) were more willing to continue treatment.

conclusionThe prognosis for most BMS patients tends to be relatively poor. Age, anxiety or depression, and fear of cancer may affect the pain prognosis of patients with BMS, whereas psychological factors may also impact the efficacy of medication.

Indexed as

Burning Mouth SyndromePatient Acceptance of Health CareAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPain MeasurementPrognosisRetrospective StudiesTreatment OutcomeBurning mouth syndromeInfluencing factorsMedication efficacyPrognosisSurveyTreatment willingness

Identifiers

PMID39994648
PMCPMC11853313

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.