ArticleBMC health services research2025
Exploring the factors influencing the timely intravitreal anti-VEGF treatment in patients with diabetic macular edema: a qualitative interview study using the COM-B model.
Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Health, hope and worry: A qualitative study of people with diabetes' experiences with anti-VEGF treatment.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Experiences and Perspectives on Diabetic Retinopathy Screening and Treatment in Mexico: A Subanalysis of the Diabetic Retinopathy Barometer Study.Ophthalmology and therapy · 2026Article
- Remote Management of Patients With Diabetic Macular Edema Receiving Long-Term Intravitreal Anti-Vascular Endothelial Growth Factor Therapy (RE-SHINE Study): Protocol for a Real-World Study.JMIR research protocols · 2026Article
- Planned vs. Performed Treatment Regimens in Diabetic Macular Edema: Real-World Evidence from the PACIFIC Study.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeTo explore the factors influencing the untimely receipt of intravitreal anti-vascular endothelial growth factor (VEGF) injections in patients with diabetic macular edema (DME), based on the capability, opportunity, and motivation-behavior (COM-B) model.
designAn exploratory qualitative study was conducted with semi-structured interviews with DME patients who had received at least one injection of anti-VEGF therapy within one year. The COM-B model was utilized to guide both data collection and analysis.
resultsThemes and subthemes were identified. Psychological capability for timely intravitreal anti-VEGF treatment included lack of relevant knowledge and choice of more convenient treatments. Social opportunity included no mention of intravitreal anti-VEGF therapy and effective doctor-patient communication; physical opportunity included unavailability of anti-VEGF and high treatment costs. Reflective motivation included lack of confidence in the efficacy and unmet expectations; automatic motivation included fear of injections, and fear of blindness.
conclusionThis study identified the facilitators and barriers that influenced the timely intravitreal anti-VEGF injections, which lays the foundation for the development of future interventions.
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