Evidence map›Paper›PMID 39994573›Full record

ArticleBMC infectious diseases2025

Sexually transmitted infections and bacterial vaginosis in women of child-bearing age in Antananarivo, Madagascar: prevalence and risk factors from a cross-sectional study.

Camille Fortas, Aina Nirina Harimanana, Solange Bienvenue Rasoanandrianina, Tsinjo Fehizoro Rasoanaivo, Hobisoa Léa Razanadranaivo, Reziky Tiandraza Mangahasimbola, Dimitri Toky Rasolon, Lala Fanomezantsoa Rafetrarivony, Tsiry Tahina Rasolofomanana, Laurah Rabarisoa and 3 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Camille FortasUnit of epidemiology and modelling of bacterial escape to antimicrobials (EMAE), Institut Pasteur, Université Paris Cité, Paris, France. camille.fortas@pasteur.fr.
Aina Nirina HarimananaUnit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Solange Bienvenue RasoanandrianinaCentre Hospitalier Universitaire de Gynécologie Obstétrique de Befelatanana, Antananarivo, Madagascar.
Tsinjo Fehizoro RasoanaivoUnit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Hobisoa Léa RazanadranaivoUnit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Reziky Tiandraza MangahasimbolaUnit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Dimitri Toky RasolonUnit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Lala Fanomezantsoa RafetrarivonyUnit of Experimental Bacteriology, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Tsiry Tahina RasolofomananaUnit of Experimental Bacteriology, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Laurah RabarisoaUnit of Experimental Bacteriology, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Bich-Tram Huynh *Unit of epidemiology and modelling of bacterial escape to antimicrobials (EMAE), Institut Pasteur, Université Paris Cité, Paris, France.
Rindra Vatosoa Randremanana *Unit of Epidemiology and Clinical Research, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Tania Crucitti *Unit of Experimental Bacteriology, Institut Pasteur de Madagascar, Antananarivo, Madagascar.

Funding

European and Developing Countries Clinical Trials 2 - EDCTP2 RIA2020I-3297
6 · The paper itself

Abstract

backgroundRecent data on sexually transmitted infections (STIs) and bacterial vaginosis (BV) in the general population of Madagascar is scarce. Our objective is to estimate the Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Mycoplasma genitalium (MG), and BV prevalence among women and to determine associated risk factors.

methodsWe recruited women aged 18-45 years consulting at a hospital in Antananarivo in a cross-sectional study. We collected socio-demographic and behavioral data. Vaginal swabs were collected for each individual. STIs were detected by qPCR and BV using the Nugent score. We explored factors associated with having an STI using logistic regressions.

resultsOf the 501 recruited women, 242 (48%) were married. Only one woman in three ever used condoms. The prevalence of CT was 11.8% (95% Confidence Interval: 9.0, 14.6), NG: 4.2% (2.4, 5.9), TV: 14.8% (11.7, 17.9), MG: 8.2% (5.8, 10.6), and BV: 39.6% (35.3, 43.9). Factors associated with an STI were having sex in exchange for favors (adjusted Odds Ratio (aOR): 4.25, 95%CI: 1.27, 16.6), BV (aOR: 2.14, 95%CI: 1.34, 3.47) or intermediate vaginal microbiota (aOR: 2.10, 95%CI: 1.19, 3.72), and being in a non-marital relationship compared to married (aOR: 1.86, 95%CI: 1.16, 2.98).

conclusionsTo address the high prevalence of STIs, prevention programs should target women who are more likely to engage in sex in exchange for favors and empower them with negotiation skills on condom use. Given the elevated prevalence of dysbiosis and its association with STIs, it is crucial to prioritize research efforts toward a comprehensive understanding of this relationship.

Indexed as

Sexually Transmitted DiseasesVaginosis, BacterialAdolescentAdultCross-Sectional StudiesFemaleHumansMadagascarMiddle AgedNeisseria gonorrhoeaePrevalenceRisk FactorsSexual BehaviorTrichomonas vaginalisVaginaYoung AdultBacterial vaginosisEpidemiologyMadagascarSexually transmitted infectionsWomen

Identifiers

PMID39994573
PMCPMC11849146

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.