ArticleInternational journal of emergency medicine2025
The association between anion gap and prognosis in patients myocardial infarction with congestive heart failure: a retrospective analysis of the MIMIC-IV database.
Article in International journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Article
- Predictive Value of 48-hour Anion Gap Fluctuations in ICU Patients with Acute Kidney Injury: An Analysis based on MIMIC Database.Current pharmaceutical design · 2026Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElevated serum anion gap at hospital admission is often linked to a poor prognosis in critically ill patients, but there is insufficient data on this correlation in patients with acute myocardial infarction accompanied by heart failure. In this study, we aimed to determine the relationship between serum admission AG and all-cause mortality in patients with acute myocardial infarction accompanied by heart failure.
methodsWe conducted a retrospective analysis of data within the MIMIC-IV database. Serum AG was collected at ICU admission, and all-cause mortality after discharge was analyzed. Multivariable Cox proportional hazards regression models and Kaplan-Meier survival curve analyses were used to assess the relationship between serum AG and myocardial infarction accompanied by heart failure as well as all-cause mortality.
resultsA total of 943 patients with acute myocardial infarction complicated by heart failure were included in the study. The all-cause mortality rate after discharge was 24.7% and 18.9%. Multivariable analysis, adjusted for potential confounders, indicated that compared to low serum AG levels (< 12 mmol/L), high serum AG levels (> 17 mmol/L) were associated with an increased risk of all-cause mortality. Similarly, Kaplan-Meier survival curves also indicated that patients with higher serum AG levels had lower survival rates. Stratified analysis further showed that the association between higher serum AG levels and in-hospital all-cause mortality was observed across different subgroups based on stratification variables.
conclusionsIn patients with acute myocardial infarction complicated by heart failure, elevated serum AG levels at ICU admission are associated with an increased risk of all-cause mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.