ArticleBMC medical imaging2025
Comparative diagnostic performance of VI-RADS based on biparametric and multiparametric MRI in predicting muscle invasion in bladder cancer.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Interobserver agreement of non-parallel transmission technology zoomed-diffusion-weighted imaging (DWI) for ordinal biparametric Vesical Imaging-Reporting and Data System (VI-RADS)-based scoring in bladder cancer lesions ≥1 cm.Quantitative imaging in medicine and surgery · 2026Article
- Added value of synthetic MRI in refining biparametric MRI VI-RADS for predicting muscle-invasive bladder cancer.Abdominal radiology (New York) · 2026Article
- Application of computed diffusion-weighted imaging in vesical imaging reporting and data system assessment for bladder cancer.Abdominal radiology (New York) · 2026Article
- Enhancing the performance of BP-MRI VI-RADS in detecting muscle-invasive bladder cancer: the potential role of supplementary quantitative parameters.Japanese journal of radiology · 2026Article
- Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer.Diagnostics (Basel, Switzerland) · 2026Review
- bp-VI-RADS combined with normalized apparent diffusion coefficient enhances diagnostic efficacy for muscle-invasive bladder cancer.Quantitative imaging in medicine and surgery · 2026Article
- The diagnostic value of biparametric magnetic resonance imaging vesical imaging-reporting and data system combined with tumor contact length for assessing muscle invasion in bladder cancer lesions scored vesical imaging-reporting and data system 3: A single-center retrospective analysis.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
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Abstract
backgroundVesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric magnetic resonance imaging (mp-MRI) performed well in diagnosing muscle-invasive bladder cancer (MIBC). However, certain cases may present challenges in determining the final VI-RADS score using only T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) sequences, especially in the absence of dynamic contrast-enhanced (DCE) imaging. This study aims to evaluates whether biparametric MRI (bp-MRI) achieve comparable diagnostic performance to mp-MRI for predicting MIBC and seeks to identify the most suitable bp-MRI criterion by establishing four specific conditions based on T2WI and DWI.
methodsA retrospective analysis was conducted on 447 patients who underwent preoperative mp-MRI. Images were evaluated according to the VI-RADS protocol by three independent readers. In the bp-DWI and bp-DWI Plus criteria, DWI was the primary sequence used for lesion assessment, while T2WI was the primary sequence for bp-T2WI and bp-T2WI Plus criteria. The Plus criteria (bp-DWI Plus and bp-T2WI Plus) assigned a final VI-RADS score of 4 when both T2WI and DWI scores were 3. The gold standard for diagnosis was histopathological evaluation after surgery. Diagnostic performance was evaluated by comparing the area under the curve (AUC), sensitivity, specificity, and inter-reader agreement using Cohen's kappa analysis.
resultsAmong 447 patients, 304 confirmed as NMIBC and 143 as MIBC. The kappa values were 0.876, 0.873, 0.873, 0.642, and 0.642 for mp-MRI, bp-DWI, bp-DWI Plus, bp-T2WI, and bp-T2WI Plus, respectively, when VI-RADS cutoff > 2. Similarly, when cutoff > 3, the kappa values were 0.848, 0.811, 0.873, 0.811, and 0.873. No significant differences were observed between mp-MRI and bp-DWI (AUC: 0.916 vs. 0.912, p = 0.498), but mp-MRI and bp-DWI had higher AUCs compared to bp-DWI Plus, bp-T2WI, and bp-T2WI Plus.
conclusionsBoth mp-MRI and bp-DWI demonstrate excellent performance in predicting MIBC, with bp-DWI being an alternative to mp-MRI.
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