ArticleObesity (Silver Spring, Md.)2025
Predictability of genetic risk score for insulin resistance is influenced by both BMI and race.
Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Association between single-point insulin sensitivity estimator and three-vessel coronary disease: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Association Between Platelet-to-Lymphocyte Ratio and Insulin Resistance in Cancer Survivors: A Cross-Sectional Study Based on the NHANES 2005 - 2018.World journal of oncology · 2025Article
- Predictability of genetic risk score for insulin resistance is influenced by both BMI and race.Obesity (Silver Spring, Md.) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe study objective was to determine whether associations between a genetic risk score (GRS) for insulin resistance (IR) and measures of insulin sensitivity differ by race and/or BMI status in African American (AA) and European American (EA) adults without diabetes.
methodsFifty-three AA and 54 EA participants were classified into "high" or "low" BMI groups using the sample median (25.9 kg/m
resultsIn EA participants, associations of GRS with HOMA-IR and the Matsuda index differed by BMI status, where the GRS was associated with IR in the high-BMI group only. In AA participants, associations from the clamp differed by BMI status, but an association was observed only in the low-BMI group.
conclusionsThese results highlight the heterogeneity of IR and support the hypothesis that the relationship between genetic predisposition for IR and obesity is race- and tissue-specific.
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Registered trials
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