Evidence map›Paper›PMID 39994429›Full record

ArticleScientific reports2025

Association of pan-immune inflammation value with mortality in patients with pulmonary embolism: a cohort study.

Weihong Zhao, Qunfen Liao, Yanxiu Feng, Fuhua Du, Zhengkai Liang, Xi Chen, Xiufen Liao, Yang Gu, Ma Zhang, Yingdong Zhang and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Weihong ZhaoDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Qunfen LiaoDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Yanxiu FengDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Fuhua DuDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Zhengkai LiangDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Xi ChenDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Xiufen LiaoDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Yang GuDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Ma ZhangDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Yingdong ZhangDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Xin LiDepartment of Emergency and Critical Care Centre, Sichuan Science City Hospital, Mianyang, Sichuan Province, China.
Feng XuDepartment of Emergency Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China. best_zwh@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pan-immune inflammation value (PIV) is associated with prognosis in immune and inflammatory diseases, and inflammation is a hallmark of pulmonary embolism (PE). Nonetheless, the link between PIV and prognosis in PE remains unclear. However, few studies have specifically focused on critically ill patients with PE in ICUs. This study retrospectively analyzed electronic health data of patients with PE from the Medical Information Mart for Intensive Care (MIMIC-IV) database. The primary outcome was 28-day ACM; secondary outcomes were 90-day, 1-year, ICU, and in-hospital mortality. The study population included 213 patients with PE. Multivariate Cox proportional hazards regression showed that elevated PIV was significantly associated with ACM at 28 days (adjusted hazard ratio [aHR]: 1.93; 95% confidence interval [CI]: 1.02-3.63) and 90 days (aHR: 1.96; 95% CI: 1.10-3.47). Further, multivariate logistic regression analysis showed that PIV was significantly and positively associated with the risk of ACM. Kaplan-Meier survival curves showed that PIV was positively associated with ACM. Subgroup and interaction analyses corroborated this correlation. PIV was significantly correlated with ACM in critically ill ICU patients with PE. This correlation highlights the potential utility of PIV for stratifying patients with PE according to their risk of death.

Indexed as

InflammationPulmonary EmbolismAgedCritical IllnessFemaleHospital MortalityHumansIntensive Care UnitsKaplan-Meier EstimateMaleMiddle AgedPrognosisProportional Hazards ModelsRetrospective StudiesCohort studiesMortalityPan-immune inflammation valuePulmonary embolism

Identifiers

PMID39994429
PMCPMC11850865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.