Evidence map›Paper›PMID 39994345›Full record

ArticleScientific reports2025

Crosado embalming related alterations in the morpho-mechanics of collagen rich tissues.

Joanna Tomlinson, Mario Scholze, Benjamin Ondruschka, Niels Hammer, Johann Zwirner

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna TomlinsonSchool of Anatomy, University of Bristol, Bristol, UK. jcltomlinson@hotmail.co.uk.
Mario ScholzeInstitute of Materials Science and Engineering, Chemnitz University of Technology, Chemnitz, Germany.
Benjamin OndruschkaInstitute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Niels HammerDepartment of Macroscopic and Clinical Anatomy, Medical University of Graz, Graz, Austria.
Johann ZwirnerInstitute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. medijo@gmx.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crosado-embalming has been successfully used as embalming technique in research and teaching for over 20 years. It is applied in biomechanical testing experiments if the fresh tissues are unavailable, e.g., for cultural, ethical, logistical or health and safety reasons. However, features of human Crosado-embalmed tissues biomechanical characteristics including its load-deformation properties in comparison to fresh tissues and its controllability through hydration fluids may be insightful and therefore need to be studied further. This study compared the uniaxial load-deformation properties and the cross-sectional area (CSA) measurements of fresh-frozen and Crosado-embalmed collagen-rich tissues, namely the iliotibial band (ITB, 16 unembalmed and 35 embalmed specimens) and cranial dura mater (DM, 60 unembalmed cadavers, and 25 embalmed specimens). The water content of 120 Crosado-embalmed ITB samples (30 cadavers) were analysed considering established rehydration treatments, including polyethylene glycol (PEG). Crosado-embalmed tissues presented an increased elastic modulus (EM) (all p < 0.050; e.g., Crosado ITB PEG only 306 ± 91 MPa vs. fresh-frozen ITB PEG only 108 ± 31 MPa; mean ± standard deviation; p < 0.001) and ultimate tensile strength (UTS) (e.g., Crosado ITB PEG only 46 ± 15 MPa vs. fresh-frozen ITB PEG only 21 ± 8 MPa; p < 0.001) when rehydrated similar to the fresh tissues. The maximum force was different for the dura mater (Crosado 25 ± 13 N vs. fresh 21 ± 20 N; mean ± standard deviation; p = 0.050) but not for the ITB. The CSA following rehydration in PEG only was decreased for Crosado-embalmed samples (3.4 ± 1.2mm

Indexed as

CollagenEmbalmingAgedBiomechanical PhenomenaCadaverDura MaterElastic ModulusFemaleHumansMaleMiddle AgedCollagenBiomechanical propertyDura materEmbalmingExtra-cellular matrixIliotibial bandPhenoxyethanolWater content

Identifiers

PMID39994345
PMCPMC11850799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.