Evidence map›Paper›PMID 39994270›Full record

ArticleScientific reports2025

Association between resting heart rate and prognosis in patients with gastric cancer.

Dong Hoon Lee, Dong-Hyuk Park, Tae Ho Lee, Edward L Giovannucci, Sung Hyun Park, Minah Cho, Yoo Min Kim, Woo Jin Hyung, Justin Y Jeon, Hyoung-Il Kim

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dong Hoon LeeDepartment of Sport Industry Studies, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Dong-Hyuk ParkDepartment of Sport Industry Studies, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Tae Ho LeeDepartment of Sport Industry Studies, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Edward L GiovannucciDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, US.
Sung Hyun ParkDepartment of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Minah ChoDepartment of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Yoo Min KimDepartment of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Woo Jin HyungDepartment of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea.
Justin Y JeonDepartment of Sport Industry Studies, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea. jjeon@yonsei.ac.kr.
Hyoung-Il KimDepartment of Surgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seoul, 03722, Seodaemun-gu, Republic of Korea. cairus@yuhs.ac.

Funding

Yonsei University 2021-22-0009Yonsei University 2024-22-0093
6 · The paper itself

Abstract

This study aimed to evaluate prognostic value of resting heart rate (RHR) in patients with gastric cancer. We analyzed 1,561 patients who underwent radical gastrectomy at Severance Hospital, Korea. RHRs were measured after surgery, and detailed medical, treatment, and lifestyle information was collected. Cox regression models were used to estimate the hazard ratios (HRs) and 95% confidence interval (95% CI) for the association between postoperative RHR and prognostic outcomes. During a median of 4 years of follow-up, we identified 174 total deaths, 92 major complications (within 30 days), 186 recurrences, and 106 gastric-cancer-specific deaths. In multivariable-adjusted models, HRs (95% CI) per 10 beats per minute increase in RHR were 1.18 (1.07-1.31) for all-cause mortality, 1.45 (1.33-1.59) for major complication within 30 days, 1.13 (1.02-1.26) for recurrence, and 1.07 (0.93-1.24) for gastric cancer-specific mortality. We consistently observed that higher postoperative RHR is associated with poor prognostic outcomes regardless of demographics, lifestyle, and cancer stage in patients with gastric cancer. In conclusion, an elevated postoperative RHR was associated with an increased risk of all-cause mortality, major complications, and recurrence in patients with gastric cancer. RHR can potentially be used to predict the prognosis of patients with gastric cancer.

Indexed as

Heart RateStomach NeoplasmsAdultAgedFemaleGastrectomyHumansMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisRepublic of KoreaHeart rateMortalityPrognosisStomach neoplasms

Identifiers

PMID39994270
PMCPMC11850771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.