Evidence map›Paper›PMID 39994235›Full record

ArticleCell death & disease2025

The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m

Gui-Yuan Song, Qing-Hua Yu, Xue-Kun Xing, Xin-Ming Fan, Si-Guang Xu, Wen-Bo Zhang, Yao-Yao Wu, Nan Zhang, Tian-Zhu Chao, Fei Wang and 6 more

Abstract read
In one paragraph

Article in Cell death & disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. The mMolecular biomedicine · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. The Roles and Implications of m6A Methylation in Radiotherapy for Gastrointestinal Tumors.Dose-response : a publication of International Hormesis Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gui-Yuan Song *Laboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Qing-Hua Yu *Laboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Xue-Kun Xing *School of Public Health, Guilin Medical University, Guilin, Guangxi, China.
Xin-Ming FanDepartment of Radiotherapy, Zaozhuang Municipal Hospital, Zaozhuang, Shandong, China.
Si-Guang XuKey Laboratory of Medical Tissue Regeneration of Henan Province, Xinxiang Medical University, Xinxiang, Henan, China.
Wen-Bo ZhangKey Laboratory of Medical Tissue Regeneration of Henan Province, Xinxiang Medical University, Xinxiang, Henan, China.
Yao-Yao WuLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Nan ZhangLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Tian-Zhu ChaoLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Fei WangLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Cheng-Shi DingLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Cun-Yang GuoLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Li MaDepartment of Radiotherapy, Zaozhuang Municipal Hospital, Zaozhuang, Shandong, China.
Chang-Ye SunKey Laboratory of Medical Tissue Regeneration of Henan Province, Xinxiang Medical University, Xinxiang, Henan, China.
Shu-Yan DuanLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China.
Ping XuLaboratory of Radiation-induced Diseases and Molecule-targeted Drugs, School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, China. 19863349848@163.com.ORCID http://orcid.org/0000-0001-9819-6870

Funding

National Science Foundation of China | National Natural Science Foundation of China-Yunnan Joint Fund (NSFC-Yunnan Joint Fund) 81773358, 11705158, U1504824
6 · The paper itself

Abstract

While apoptotic cell death is known to be central to the pathogenesis of radiation-induced liver injury (RILI), the mechanistic basis for this apoptotic activity remains poorly understood. N

Indexed as

AdenosineLiverMethyltransferasesNerve Tissue ProteinsRNA-Binding ProteinsRNA, Long NoncodingRNA Splicing FactorsAnimalsApoptosisHumansMethylationAdenosineMEG3 non-coding RNA, humanMethyltransferasesMETTL3 protein, humanNerve Tissue ProteinsN-methyladenosineRNA-Binding ProteinsRNA, Long NoncodingRNA Splicing FactorsYTHDC1 protein, human

Identifiers

PMID39994235
PMCPMC11850776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.