Evidence map›Paper›PMID 39994114›Full record

ArticleBiological trace element research2025

Relationship Between the Single Nucleotide Polymorphism A35C in the Cu/Zn-Superoxide Dismutase-1 Gene and Glycemic Control in Individuals with Type 2 Diabetes Mellitus.

Gabrielli Barbosa de Carvalho, Paula Nascimento Brandão-Lima, Ramara Kadija Fonseca Santos, Vivianne de Sousa Rocha, Alan Santos Oliveira, Beatriz da Cruz Santos, Cynthia Batista Santos, Aline Rocha Reis, Carla Soraya Costa Maia, Ana Mara de Oliveira E Silva and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gabrielli Barbosa de CarvalhoDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Paula Nascimento Brandão-LimaNutritional Biochemistry Laboratory, Department of Nutrition, Center for Biological and Health Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Ramara Kadija Fonseca SantosDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Vivianne de Sousa RochaDepartment of Nutrition, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
Alan Santos OliveiraPost-Graduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Beatriz da Cruz SantosDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Cynthia Batista SantosDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Aline Rocha ReisDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Carla Soraya Costa MaiaDepartment of Nutrition, State University of Ceará, Fortaleza, Ceará, Brazil.
Ana Mara de Oliveira E SilvaDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil.
Liliane Viana PiresDepartment of Nutrition, Nutrition Sciences Post-Graduate Program, Federal University of Sergipe, Marcelo Deda Chagas Avenue, S/n - Jardim Rosa Elze, São Cristóvão, Sergipe, 49107-230, Brazil. lvianapires@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperglycemia in type 2 diabetes mellitus (T2DM) increases oxidative stress. Furthermore, the presence of the single nucleotide polymorphism A35C (SNP A35C) in Cu/Zn-superoxide dismutase1 (SOD1) gene is closely related to this increase in oxidative stress and the development and progression of T2DM and its complications. This study aimed to evaluate the association between SNP A35C (rs2234694) genotypes and glycemic control in T2DM individuals. A total of 110 individuals were evaluated for anthropometric parameters, body composition, glycemic metabolism markers (fasting serum glucose, %Hb

Indexed as

Diabetes Mellitus, Type 2Glycemic ControlPolymorphism, Single NucleotideSuperoxide Dismutase-1AdultAgedBlood GlucoseFemaleGenotypeHumansMaleMiddle AgedBlood GlucoseSOD1 protein, humanSuperoxide Dismutase-1Insulin resistanceOxidative stressSingle nucleotide polymorphismType 2 diabetes mellitus

Identifiers

PMID39994114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.