Evidence map›Paper›PMID 39994082›Full record

ArticleNeurosurgical review2025

Incidence and predictors of Woven EndoBridge (WEB) shape modification following treatment of intracranial aneurysms in a large multicenter study.

Nimer Adeeb, Hamza Adel Salim, Basel Musmar, Assala Aslan, Christian Swaid, Miguel Cuellar, Mahmoud Dibas, Nicole M Cancelliere, Jose Danilo Bengzon Diestro, Oktay Algin and 77 more

Abstract readMulticenter Study
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

87 authors.

Nimer AdeebDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA. nimer_adeeb@hotmail.com.
Hamza Adel SalimDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Basel MusmarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Assala AslanDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Christian SwaidDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Miguel CuellarDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Mahmoud DibasDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Nicole M CancelliereNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Jose Danilo Bengzon DiestroNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Oktay AlginDepartment of Radiology, Medical Facultyof , Ankara University, Ankara, Turkey.
Sherief GhozyDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
Sovann V LayDepartment of Neuroradiology, Centre Hospitalier de Toulouse, Toulouse, France.
Adrien GuenegoDepartment of Neuroradiology, Hôpital Universitaire Erasme, Brussels, Belgium.
Leonardo RenieriDepartment of Neuroradiology, Ospedale Careggi Di Firenze, Florence, Italy.
Joseph CarnevaleDepartment of Neurosurgery and Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospitaland , New York, NY, USA.
Guillaume SaliouDepartment of Neuroradiology, Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland.
Panagiotis MastorakosDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Kareem El NaamaniDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Eimad ShotarDepartment of Neuroradiology, Hôpital Pitié-Salpêtrière, Paris, France.
Markus MöhlenbruchDepartment of Neuroradiology, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Michael KralDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.
Charlotte ChungDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Mohamed M SalemDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Ivan LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Paul M ForemanDepartment of Neurosurgery, Orlando Health Neuroscience and Rehabilitation Institute, Orlando, FL, USA.
Hamza ShaikhDepartment of Neuroradiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
Vedran ŽupančićDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Muhammad U HafeezDepartment of Neurosurgery, Barrow , Neurological Institute, Phoenix, AZ, USA.
Joshua CatapanoDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Muhammad WaqasDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Muhammet ArslanDeparment of Radiology, Pamukkale University, Denizli, Turkey.
Onur ErgunDepartment of Radiology, Medical Facultyof , Ankara University, Ankara, Turkey.
James D RabinovNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Yifan RenDepartment of Neuroradiology, Austin Health, Heidelberg, VIC, Australia.
Clemens M SchirmerDepartment of Neurosurgery and Radiology, Geisinger Hospital, Danville, PA, USA.
Mariangela PianoDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milan, Italy.
Anna L KühnDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, MA, USA.
Caterina MichelozziDepartment of Neuroradiology, Ospedale San Raffaele, Milan, Italy.
Robert M StarkeDepartment of Neurosurgery, University of Miami, Miami, FL, USA.
Ameer HassanDepartment of Neuroradiology, Valley Baptist Neuroscience Institute, Harlingen, TX, USA.
Mark OgilvieDeparments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Anh NguyenDepartment of Neuroradiology, University Hospital of Basel, Basel, Switzerland.
Jesse JonesDeparments of Neurosurgery and Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Waleed BrinjikjiDepartments of Radiology and Neurosurgery, Mayo Clinic, Rochester, MN, USA.
Marie T NawkaDepartment of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Marios PsychogiosDepartment of Neuroradiology, University Hospital of Basel, Basel, Switzerland.
Christian UlfertDepartment of Neuroradiology, Universitätsklinikum Heidelberg, Heidelberg, Germany.
Bryan PukenasDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Jan-Karl BurkhardtDepartment of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USA.
Thien HuynhDepartments of Radiology and Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Juan Carlos Martinez-GutierrezDepartment of Neuroradiology, University of Texas Health Science Center at Houston, Houston, TX, USA.
Muhammed Amir EssibayiDepartment of Neurosurgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Sunil A ShethDepartment of Neuroradiology, University of Texas Health Science Center at Houston, Houston, TX, USA.
Diana SlawskiDepartment of Radiology, Division of Neuroimaging and Neurointervention, Stanford University School of Medicine, Stanford, CA, USA.
Rabih TawkDepartments of Radiology and Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.
Benjamin PulliDepartment of Radiology, Division of Neuroimaging and Neurointervention, Stanford University School of Medicine, Stanford, CA, USA.
Boris LubiczDepartment of Neuroradiology, Hôpital Universitaire Erasme, Brussels, Belgium.
Pietro PanniDepartment of Neuroradiology, Ospedale San Raffaele, Milan, Italy.
Ajit S PuriDepartment of Neuroradiology, UMass Memorial Hospital, Worcester, MA, USA.
Guglielmo PeroDepartment of Neuroradiology, Ospedale Niguarda Cà Granda, Milan, Italy.
Eytan RazDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Christoph J GriessenauerDepartment of Neurosurgery, Christian Doppler University Hospital & Institute of Neurointervention, Salzburg, Austria.
Hamed AsadiDepartments of Radiology & Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Adnan SiddiquiDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Elad I LevyDepartment of Neurosurgery, State University of New York at Buffalo, Buffalo, NY, USA.
Neil HaranhalliDepartment of Neurosurgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
David AltschulDepartment of Neurosurgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Andrew F DucruetDepartment of Neurosurgery, Barrow , Neurological Institute, Phoenix, AZ, USA.
Felipe C AlbuquerqueDepartment of Neurosurgery, Barrow , Neurological Institute, Phoenix, AZ, USA.
Robert W RegenhardtNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Christopher J StapletonNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Peter KanDepartment of Neurosurgery, UTMB and Baylor School of Medicine, Houston, TX, USA.
Vladimir KalousekDepartment of Neuroradiology, Clinical Hospital Center 'Sisters of Mercy', Zagreb, Croatia.
Pedro LylykDepartment of Neuroradiology, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Srikanth BodduDepartment of Neurosurgery and Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospitaland , New York, NY, USA.
Jared KnopmanDepartment of Neuroradiology, Centre Hospitalier Vaudois de Lausanne, Lausanne, Switzerland.
Stavropoula I TjoumakarisDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Pascal M JabbourDepartment of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Frédéric ClarençonDepartment of Neuroradiology, Hôpital Pitié-Salpêtrière, Paris, France.
Nicola LimbucciDepartment of Neurosurgery and Neuroradiology, Weill Cornell School of Medicine, New York Presbyterian Hospitaland , New York, NY, USA.
Vivek YedavalliDepartment of Radiology, Division of Neuroradiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Max WintermarkNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Vitor Mendes PereiraNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Aman B PatelNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
Hugo H Cuellar-SaenzDepartment of Neurosurgery and Interventional Neuroradiology, Louisiana State University, Shreveport, LA, USA.
Adam A DmytriwNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Worldwide Web Workgroup

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Woven EndoBridge (WEB) device is FDA-approved for the treatment of bifurcation aneurysms. Despite its wide popularity, it has been under scrutiny for its association with potential aneurysm recanalization and retreatment due to device shape modification. This study aims to analyze the shape modification rate of WEB devices and identify factors associated with this phenomenon, as well as its correlation with aneurysm retreatment. We conducted a retrospective review of the WorldWide WEB Consortium database, including adult patients treated for intracranial aneurysms with the WEB device. We assessed aneurysm occlusion using the WEB Occlusion Scale and defined WEB shape modification as a percentage reduction in the distance between two WEB markers. Logistic regression and Cox proportional hazards models were utilized to evaluate predictors of shape modification and retreatment. Kaplan-Meier curves were used to estimate the time-dependent probability of no or minor shape modification. A total of 405 patients were analyzed, with minor and major shape modification occurring in 31.4% and 10.1% of cases, respectively. Major shape modification was associated with lower rates of adequate occlusion (70.7%) compared to no or minor shape modification (86.6%) and a higher rate of retreatment (26.8% vs. 8.1%). Predictors of major shape modification included the presence of daughter sac, bifurcation aneurysms, absence of immediate flow stagnation, and a WEB width minus aneurysm width ratio ≤ 0.5. The probability of no or minor shape modification declined within the first 25 months and stabilized thereafter. WEB device shape modification is a significant predictor of aneurysm occlusion efficacy and retreatment. Recognizing the factors influencing shape modification can guide treatment decisions and follow-up protocols to improve patient outcomes.

Indexed as

Endovascular ProceduresIntracranial AneurysmStentsAdultAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesTreatment OutcomeEmbolizationEndovascularIntracranial aneurysmShape modificationWEBWoven EndoBridge

Identifiers

PMID39994082
PMCPMC11850463

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