Evidence map›Paper›PMID 39994026›Full record

Observational studyCardiovascular and interventional radiology2025

Radiofrequency Ablation Versus Thoracoscopic Sublobar Resection for the Treatment of Pulmonary Ground Glass Nodules: A Retrospective Observational Study.

Shunjin Zhao, Lu Shen, Xiaoyi Tong, Xiaobin Jiang, Hongchen Li, Jun Zhao, Jianjun Wu, Shizhen Zhang, Jianying Zhou

Abstract readObservational StudyComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Observational study in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shunjin Zhao *Department of Respiratory and Critical Care Medicine, Zhejiang Provincial Clinical Research Center for Respiratory Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China.
Lu Shen *Department of Breast Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Xiaoyi TongDepartment of Pharmacy, Lanxi People's Hospital, Jinhua, Zhejiang, China.
Xiaobin JiangDepartment of Radiology, Lanxi People's Hospital, Jinhua, Zhejiang, China.
Hongchen LiDepartment of Thoracic Surgery, Lanxi People's Hospital, Jinhua, Zhejiang, China.
Jun ZhaoDepartment of Respiration, Zhejiang Medical & Health Group Hangzhou Hospital, Hangzhou, Zhejiang, China.
Jianjun WuDepartment of Radiology Intervention, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Shizhen ZhangDepartment of Breast Surgery and Oncology, Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jianying ZhouDepartment of Respiratory and Critical Care Medicine, Zhejiang Provincial Clinical Research Center for Respiratory Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, Zhejiang, China. zjyhz@zju.edu.cn.

Funding

Jinhua Major (key) Scientific and Technological Research Program Project 2021-3-015National Natural Science Foundation of China 82202838,82473005Zhejiang Provincial Medical and Health Plan Project 2022KY288
6 · The paper itself

Abstract

purposeA variety of treatments options for pulmonary ground glass nodules (GGNs) are currently under investigation. This study aimed to retrospectively compare the safety and efficacy of two therapeutic concepts, radiofrequency ablation (RFA) and thoracoscopic sublobar resection, in the treatment of patients with resectable pulmonary GGNs. MATERIALS AND

methodsThis bi-center retrospective study included patients with resectable pulmonary GGNs who received either thoracoscopic sublobar resection or percutaneous computed tomography (CT)-guided RFA. Patients' clinical outcomes were compared between the two groups.

resultsBetween November 2019 and June 2023, a total of 71 patients were included, with 34 patients undergoing CT-guided RFA after refusing surgery, and 37 patients receiving thoracoscopic sublobar resection. No local recurrence or distant metastasis was observed in either group during the follow-up period (24 (interquartile range, 17.5-34.0) months for sublobectomy group and 30 (interquartile range, 17.5-38.75) months for RFA group). Compared to the thoracoscopic sublobar resection group, the RFA group had significantly fewer postoperative complications according to the Clavien-Dindo classification, particularly a lower incidence of pleural effusion (P < 0.001). The overall hospital stay length was also significantly shorter in the RFA patients (1 day versus 8 days, P < 0.001).

conclusionsThis limited series suggests that percutaneous CT-guided RFA may be a safe and effective treatment option for patients with resectable pulmonary GGNs who refuse surgical intervention.

Indexed as

Lung NeoplasmsMultiple Pulmonary NodulesPneumonectomyRadiofrequency AblationThoracic Surgery, Video-AssistedThoracoscopyAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRadiography, InterventionalRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeGround glass nodules (GGNs)Radiofrequency ablation (RFA)Thoracoscopic sublobar resection

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.