SynthesisEuropean journal of applied physiology2025
The effects of normobaric hypoxic resistance training on muscle strength in healthy adults.
Synthesis in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Influence of Normobaric Hypoxia on Maximal Force Production Following High-Intensity Resistance Circuit Training.Journal of functional morphology and kinesiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Normobaric hypoxic resistance training (NHRT) has emerged as a novel approach to enhancing muscle strength, potentially offering advantages over conventional resistance training. However, its efficacy in healthy adults remains uncertain. This systematic review and meta-analysis aimed to evaluate the effects of NHRT on muscle strength indicators, including one-repetition maximum (1RM), isometric strength, and isokinetic strength, in healthy adults.
methodsFollowing PRISMA 2020 guidelines, four databases (PubMed, Web of Science, SportDiscus, and CNKI) were searched from inception to October 25, 2024, for randomized controlled trials. Study quality was assessed using the Cochrane Risk of Bias tool. Effect sizes were calculated using Review Manager 5.4.
resultsA total of 22 RCTs involving 487 healthy adults were included. The meta-analysis revealed a significant small-to-moderate improvement in 1RM (SMD = 0.22, 95% CI [0.06, 0.38]) but no statistically significant effects on isometric strength (SMD = 0.32, 95% CI [-0.05, 0.70]) and isokinetic strength (SMD = 0.25, 95% CI [-0.11, 0.62]). Subgroup analyses indicated that oxygen concentrations of 14-16% and training loads of 60-80% 1RM produced the most substantial gains, particularly among untrained participants.
conclusionsNHRT is a promising strategy for enhancing 1RM in healthy adults, with its effectiveness influenced by hypoxic levels, training load, and baseline training status. Optimal outcomes were observed at oxygen concentrations of 14-16% and moderate training loads (60-80% 1RM), particularly in untrained individuals. Further high-quality studies are warranted to confirm these outcomes and explore the underlying mechanisms.Registration number on PROSPEROCRD42024547100.
Indexed as
Identifiers
39994007What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.