Evidence map›Paper›PMID 39993827›Full record

ArticleClinical medicine & research2024

Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram.

Matthew Postolowski, Omair Shakil, Lintu Ramachandran, Chethan Venkatasubb Rao

Abstract readCase Reports
In one paragraph

Article in Clinical medicine & research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew PostolowskiDepartment of Neurology, Baylor College of Medicine, Houston, Texas.
Omair ShakilDepartment of Neurology, Baylor College of Medicine, Houston, Texas.
Lintu RamachandranDepartment of Neurology, Baylor College of Medicine, Houston, Texas linturam@gmail.com.
Chethan Venkatasubb RaoDepartment of Neurology and Neurosurgery, Vascular Neurology and Neurocritical Care, Baylor College of Medicine, Houston, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS) is a relatively rare and underdiagnosed neurological condition that has similar clinical presentation to other neurological emergencies. Antidepressants such as selective serotonin reuptake inhibitors can be a secondary cause of RCVS. We present the case of a healthy young woman, with long term escitalopram use, who presented with bilateral neurological deficits and was found to have RCVS, whose symptoms improved remarkably after intra-arterial calcium channel blocker treatment. We discuss risk factors, theorized mechanisms, presentation, diagnostic tools, and management of RCVS. Our case should serve as a corollary for physicians to consider RCVS as a differential diagnosis for thunderclap headache, especially in patients with selective serotonin reuptake inhibitor use.

Indexed as

CitalopramEscitalopramSelective Serotonin Reuptake InhibitorsVasoconstrictionVasospasm, IntracranialAdultCalcium Channel BlockersFemaleHumansSyndromeCalcium Channel BlockersCitalopramEscitalopramSelective Serotonin Reuptake InhibitorsRCVSReversible vasoconstriction syndromeSSRI adverse eventsSSRI side effects

Identifiers

PMID39993827
PMCPMC11849965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.