ArticleJournal of advanced research2025
Enhancing maize resistance to Fusarium verticillioides through modulation of cell wall structure and components by ZmXYXT2.
Article in Journal of advanced research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Multiplexed Engineering of Disease Resistance and Lodging Tolerance in Wheat Via a Single Xylan Modifying Glycosyltransferase.Plant biotechnology journal · 2026Article
- Plant Regeneration: Influencing Factors, Regulatory Networks, and Epigenetic Mechanisms.International journal of molecular sciences · 2026Review
- From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A new plant SUMO ligase, MPEL1, synergizes with MAPK16 to regulate resistance against Fusarium pathogens.The EMBO journal · 2026Article
- Identification of NovelMicroorganisms · 2026Article
- Integrating BSA-Seq and RNA-Seq to Identify Major QTLs and Candidate Genes Conferring Resistance to Fusarium Ear Rot in Maize.Plants (Basel, Switzerland) · 2026Article
- The Candidate Effector Cgmas2 Orchestrates Biphasic Infection ofInternational journal of molecular sciences · 2026Article
- Advances in genetic and molecular mechanisms of crop resistance to stalk rot.Stress biology · 2026Review
- Isolation, identification, and genomic analysis ofFrontiers in microbiology · 2026Article
- From Morphology to Multi-Omics: A New Age of Fusarium Research.Pathogens (Basel, Switzerland) · 2025Review
- The FvHOG1 pathway is essential for stress responses, fungicide resistance, fumonisin B1 production and pathogenesis in Fusarium verticillioides.Crop health · 2025Article
- Different strategies of altering the cell wall to study the impact that these introduced changes have on plant resistance to pathogens.Frontiers in plant science · 2025Review
- Unveiling the molecular arsenal: genome sequencing andFrontiers in plant science · 2025Article
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12 authors.
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Abstract
introductionFusarium verticillioides (F. verticillioides) is a prevalent phytopathogen that incites severe diseases in maize, resulting in substantial reductions in grain yield and quality. Despite its widespread impact, the genetic mechanisms underlying resistance to this pathogen remain elusive, with only a limited of resistant genes having been identified to date.
objectivesCharacterize the function of ZmXYXT2 encoding a putative xylan xylosyltransferase in maize defense against F. verticillioides-induced diseases.
methodsReal-time quantitative PCR and transitory transformation of maize protoplasts were conducted to analyze the expression pattern and subcellular localization of ZmXYXT2. The zmxyxt2 mutant, sourced from an ethyl methanesulfonate mutagenesis library, and the ZmXYXT2-overexpressing plants, generated via Agrobacterium tumefaciens-mediated transformation, were utilized for artificial inoculation with F. verticillioides followed by disease severity assessments. Phenotypic assessments, cytological observations, analysis of cell wall components, and histochemical staining were performed to elucidate the regulatory mechanisms of ZmXYXT2.
resultsThe absence of ZmXYXT2 renders maize vulnerable to F. verticillioides-caused seedling blight, stalk rot, ear rot and seed rot, along with a notable increase in fumonisin B1 accumulation. Conversely, maize plants overexpressing ZmXYXT2 exhibited significantly heightened immunity to these diseases. Moreover, overexpression of ZmXYXT2 results in notable changes in the composition of maize cell walls, specifically increasing the levels of arabinose, xylose and ferulic acid. These alterations lead to cell wall thickening, effectively barring the intracellular invasion and colonization of F. verticillioides, thereby halting pathogen dissemination between cells. Intriguingly, maize plants overexpressing ZmXYXT2 exhibit enhanced stem strength without compromising yield-related traits.
conclusionZmXYXT2 provides maize with resistance to multiple diseases triggered by F. verticillioides and mitigates the accumulation of fumonisin B1. Our study presents a novel approach to bolster maize comprehensive resistance against F. verticillioides-induced diseases by modifying cell wall composition to strengthen its natural defenses.
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