Evidence map›Paper›PMID 39993388›Full record

ArticlePsychotherapy and psychosomatics2025

Efficacy of Cognitive Behavioral Therapy and Acceptance- and Mindfulness-Based Treatments in Adults with Bodily Distress: A Network Meta-Analysis.

Frederic Maas Genannt Bermpohl, Alexandra Martin

Abstract readNetwork Meta-Analysis
In one paragraph

Article in Psychotherapy and psychosomatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Frederic Maas Genannt BermpohlSchool of Human and Social Sciences, Clinical Psychology and Psychotherapy, University of Wuppertal, Wuppertal, Germany.
Alexandra MartinSchool of Human and Social Sciences, Clinical Psychology and Psychotherapy, University of Wuppertal, Wuppertal, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMany physical complaints cause long-term bodily distress. Meta-analyses show that cognitive behavioral therapy (CBT) and acceptance- and mindfulness-based treatments (AMBT) reduce somatic symptom severity, but evidence on differential efficacy is limited. This study evaluates the efficacy of CBT and AMBT for bodily distress (e.g., somatoform disorders, functional somatic syndromes, and related disorders).

methodsA network meta-analysis of randomized controlled trials on adults with bodily distress compared CBT and AMBT either directly or with nonspecific control groups. Cohen's d based on between-group effect sizes was aggregated using a random effects model. Primary outcome was somatic symptom severity; secondary outcomes included depression, anxiety, and perceived health status.

resultsBased on 74 studies (N = 8,277), CBT (d = -0.50, 95% CI, -0.70 to -0.29; between-group effect sizes vs. wait-list [WL]) and AMBT (d = -0.55, 95% CI, -1.06 to -0.23; between-group effect sizes vs. WL) were equally effective in reducing somatic symptoms at posttreatment. AMBT were more effective than CBT in reducing depression (d = -0.31, 95% CI, -0.58 to -0.04; between-group effect sizes) and anxiety (d = -0.42, 95% CI, -0.73 to -0.11; between-group effect sizes) posttreatment. At long-term follow-up, effects were partly maintained; AMBT remained more effective than CBT for anxiety, with no differential effects for other outcomes.

conclusionsBoth treatments showed benefits compared to various controls. Evidence suggests potential differential treatment effects, indicating some patient groups may benefit more from AMBT. Clinicians should view CBT as foundational but remain open to variations, especially for comorbid pathology.

Indexed as

Acceptance and Commitment TherapyCognitive Behavioral TherapyMedically Unexplained SymptomsMindfulnessSomatoform DisordersAdultAnxietyDepressionHumansRandomized Controlled Trials as TopicTreatment OutcomePersistent physical symptomsPsychological treatmentsSomatic symptom disorderSomatoform disorderTreatment evaluation

Identifiers

PMID39993388
PMCPMC12060822

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.