Evidence map›Paper›PMID 39993261›Full record

ArticleBiomacromolecules2025

Biomembranes Based on Potato Starch Modified by Dry Heating Treatment: One Sustainable Strategy to Amplify the Use of Starch as a Biomaterial.

Pedro Augusto Invernizzi Sponchiado, Maryanne Trafani Melo, Juçara G Cominal, Milena Martelli Tosi, Pietro Ciancaglini, Ana Paula Ramos, Bianca Chieregato Maniglia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro Augusto Invernizzi SponchiadoDepartment of Physical Chemistry, Institute of Chemistry of São Carlos (IQSC), University of São Paulo (USP), São Carlos, São Paulo 13566-590, Brazil.
Maryanne Trafani MeloDepartment of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto (FFCLRP), University of São Paulo (USP), Ribeirão Preto, São Paulo 14040-901, Brazil.
Juçara G CominalDepartment of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto (FFCLRP), University of São Paulo (USP), Ribeirão Preto, São Paulo 14040-901, Brazil.
Milena Martelli TosiDepartment of Food Engineering, Faculty of Animal Science and Food Engineering, Postgraduate Programme in Materials Science and Engineering, University of São Paulo, 13635-900 Pirassununga, São Paulo, Brazil.
Pietro CiancagliniDepartment of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto (FFCLRP), University of São Paulo (USP), Ribeirão Preto, São Paulo 14040-901, Brazil.
Ana Paula RamosDepartment of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto (FFCLRP), University of São Paulo (USP), Ribeirão Preto, São Paulo 14040-901, Brazil.ORCID 0000-0001-6200-8989
Bianca Chieregato ManigliaDepartment of Physical Chemistry, Institute of Chemistry of São Carlos (IQSC), University of São Paulo (USP), São Carlos, São Paulo 13566-590, Brazil.ORCID 0000-0003-4174-5474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exceptional biocompatibility of polymeric membranes drives their use in biomaterials, but structural modifications are needed to improve their mechanical properties. This study investigated dry heating treatment (DHT) as an ecofriendly and cost-effective approach to modifying potato starch for biomembrane fabrication. DHT-treated starch (2 h) produced biomembranes with a denser structure, smoother surfaces, and significantly improved mechanical properties, including higher tensile strength (∼6×), rigidity (∼15×), and relative crystallinity (∼2×) while reducing flexibility (∼5×), compared to native starch membranes. These membranes also exhibited lower moisture content, reduced hydrophilicity, higher surface energy, decreased biodegradability, and enhanced bioactivity, as shown by hydroxyapatite formation in simulated body fluid. Importantly, they were nontoxic to osteoblasts, emphasizing their potential for medical applications. This study highlights DHT as a sustainable and innovative method for modifying starch to develop advanced biomaterials for medical applications.

Indexed as

Biocompatible MaterialsMembranes, ArtificialSolanum tuberosumStarchAnimalsHot TemperatureHumansMiceOsteoblastsTensile StrengthBiocompatible MaterialsMembranes, ArtificialStarch

Identifiers

PMID39993261
PMCPMC11898047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.