Evidence map›Paper›PMID 39993184›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Revisiting lipid nanoparticle composition and structure: A critical take on simulation approaches.

Marius F W Trollmann, Paolo Rossetti, Rainer A Böckmann

Abstract readLetter
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Decoding pH-Driven Phase Transition of Lipid Nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Reply to Trollmann et al.: Perspective on LNP structure and simulation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marius F W TrollmannComputational Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91058, Germany.
Paolo RossettiComputational Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91058, Germany.
Rainer A BöckmannComputational Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91058, Germany.ORCID 0000-0002-9325-5162

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39993184
PMCPMC11892627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.