Evidence map›Paper›PMID 39993029›Full record

ArticleJournal of neurophysiology2025

Excellent test-retest reliability of perturbation-evoked cortical responses supports feasibility of the balance N1 as a clinical biomarker.

Jasmine L Mirdamadi, Alex Poorman, Gaetan Munter, Kendra Jones, Lena H Ting, Michael R Borich, Aiden M Payne

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jasmine L MirdamadiDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.ORCID 0000-0001-6438-4451
Alex PoormanDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.
Gaetan MunterDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.
Kendra JonesDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.
Lena H TingDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.ORCID 0000-0001-6854-9444
Michael R BorichDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, Georgia, United States.ORCID 0000-0001-9897-9867
Aiden M PayneDepartment of Psychology, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0001-7623-9411

Funding

Neuromechanical Modeling of Postural Responses:Mechanisms of Balance Impairments in Parkinson's DiseaseR01HD046922 · NICHD · GEORGIA INSTITUTE OF TECHNOLOGY · PI Michael Robert Borich, Lena H Ting · 2004 to 2026
$7.7M
Individual-specific engagement of cortical resources for standing balance control in aging and post strokeR01AG072756 · NIA · EMORY UNIVERSITY · PI Michael Robert Borich, Lena H Ting · 2022 to 2026
$3.0M
NIA NIH HHS R01 AG072756NICHD NIH HHS R01 HD046922
6 · The paper itself

Abstract

There is a growing interest in measuring cortical activity during balance control for understanding mechanisms of impaired balance with aging and neurological dysfunction. The most well-characterized electrophysiological signal elicited by a balance disturbance is the perturbation-evoked N1 potential. We previously found associations between the N1 and balance ability, suggesting it may be a potential biomarker of balance health. However, a potential biomarker will be limited by its reliability and clinical feasibility, which has yet to be established. Here, we characterized the reliability of the balance N1 within and between sessions over a 1-wk interval in 10 younger and 14 older adults, and over a 1-year interval in a subset of older adults (

Indexed as

Cerebral CortexElectroencephalographyEvoked PotentialsPostural BalanceAdultAgedAgingBiomarkersFeasibility StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsYoung AdultBiomarkersagingEEGinternal consistencyposturepsychometrics

Identifiers

PMID39993029
PMCPMC12244522

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.