ArticlePloS one2025
Interventions to improve adherence/compliance to home noninvasive positive pressure ventilation in stable hypercapnic chronic obstructive pulmonary disease patients: A systematic review protocol.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
introductionChronic obstructive pulmonary disease (COPD) is a prevalent condition often leading to chronic hypercapnic respiratory failure in its advanced stages. Home noninvasive positive pressure ventilation (Home-NIPPV) has emerged as a key therapeutic strategy for managing stable hypercapnic COPD patients, improving survival rates, and enhancing quality of life. Despite these benefits, patient adherence/compliance to Home-NIPPV remains a significant challenge, hindered by various barriers. The present paper is a protocol of a systematic review that aims to identify and evaluate interventions designed to improve adherence/compliance to Home-NIPPV in stable hypercapnic COPD patients.
methodsThe protocol is developed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines and was registered in PROSPERO (CRD42024581616). A comprehensive literature search across PubMed, Scopus and Cochrane Library will be conducted. Eligible studies will include randomized controlled trials that focus on interventions that aims to improve adherence/compliance to Home-NIPPV in stable hypercapnic COPD patients. Data extraction will be meticulously carried out by two independent reviewers. The Joanna Briggs Institute critical appraisal tool will be utilized to assess the quality and risk of bias of the included studies. The findings of this systematic review will be synthesized to provide a thorough understanding of effective strategies to enhance adherence/compliance to Home-NIPPV in stable hypercapnic COPD patients.
conclusionThe results of this review could inform clinical practice and guide the development of targeted strategies to improve adherence/compliance to Home-NIPPV and consequently outcomes in stable hypercapnic COPD patients. REGISTRATION: This protocol was registered in the International Prospective Register of Systematic Reviews under the reference code CRD42024581616.
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