Evidence map›Paper›PMID 39992804›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

The Transcription Factor WFZP Interacts with the Chromatin Remodeler TaSYD to Regulate Root Architecture and Nitrogen Uptake Efficiency in Wheat.

Dejie Du, Zhaoju Li, Zihao Jiang, Jun Yuan, Xiangyu Zhang, Huanhuan Zhao, Lulu Tian, Yunjie Liu, Renhan Li, Fei He and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Dejie DuFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Zhaoju LiFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Zihao JiangFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Jun YuanFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Xiangyu ZhangFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Huanhuan ZhaoFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Lulu TianFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Yunjie LiuFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Renhan LiFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Fei HeFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Xiongtao LiFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Wensheng KeFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Lingling ChaiFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Jie LiuFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Mingming XinFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Yingyin YaoFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Qixin SunFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.
Jiewen XingFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-3503-0739
Zhongfu NiFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China.

Funding

China Postdoctoral Science Foundation 2022M723431Chinese Universities Scientific Fund 2024TC161National Natural Science Foundation of China 32201824National Natural Science Foundation of China U22A6009Pinduoduo-China Agricultural University Research Fund PC2023A01003
6 · The paper itself

Abstract

The root architecture is crucial for the robust growth and nutrient absorption in cereals. However, it is urgent to identify the factors that simultaneously optimize root architecture and nutrient utilization in wheat. In this study, a beneficial role of the class II AP2/ERF transcription factor WHEAT FRIZZY PANICLE (WFZP) on lateral root number (LRN), root length (RL), and nitrogen utilization is revealed. In addition, interactors of WFZP including TaSYD are identified, as a subunit of the chromatin remodeling complex. The Tasyd mutants show a significant reduction in LRN, RL, and nitrogen uptake efficiency, resembling the phenotype of wfzp mutants. Furthermore, it is revealed that the WFZP-TaSYD module promotes the expression of root development and nitrate uptake-related genes by modulating chromatin accessibility and histone modifications. Finally, an elite allele (WFZP-A-I) associated with improved LRN and thousand-grain weight (TGW) is identified. Hence, these findings not only unveil the mechanisms underlying the coordination of root development and nitrogen uptake efficiency, but also provide valuable targets for breeding high-yield crops.

Indexed as

Chromatin Assembly and DisassemblyNitrogenPlant ProteinsPlant RootsTranscription FactorsTriticumGene Expression Regulation, PlantNitrogenPlant ProteinsTranscription Factorslateral root numbernitrogen uptake efficiencyTaSYDWFZPwheat

Identifiers

PMID39992804
PMCPMC12005776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.