Evidence map›Paper›PMID 39992777›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2025

Getting to yes: Pilot sequential multiple assignment randomized trial of motivational enhancement interventions targeting preexposure prophylaxis use in sexual minority men who use stimulants.

Leah Davis Ewart, Michaela E Larson, Delaram Ghanooni, Rachel Verhagen, Jennifer Manuel, Kathryn McCollister, Erminia Fardone, Britt DeVries, Samantha Dilworth, Makayla Blackstock and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leah Davis EwartRobert Stempel College of Public Health and Social Work, Florida International University.ORCID 0000-0002-8143-4630
Michaela E LarsonRobert Stempel College of Public Health and Social Work, Florida International University.
Delaram GhanooniRobert Stempel College of Public Health and Social Work, Florida International University.
Rachel VerhagenDepartment of Psychology, College of Arts and Sciences, University of Miami.
Jennifer ManuelDepartment of Psychiatry, University of California, San Francisco.
Kathryn McCollisterMiller School of Medicine, University of Miami.ORCID 0000-0003-4336-9791
Erminia FardoneMiller School of Medicine, University of Miami.
Britt DeVriesMiller School of Medicine, University of Miami.
Samantha DilworthMiller School of Medicine, University of Miami.
Makayla BlackstockRobert Stempel College of Public Health and Social Work, Florida International University.
Susanne Doblecki-LewisMiller School of Medicine, University of Miami.
Inbal Nahum-ShaniInstitute for Social Research, University of Michigan.
Christian GrovGraduate School of Public Health and Health Policy, City University of New York.
Adam W CarricoRobert Stempel College of Public Health and Social Work, Florida International University.ORCID 0000-0002-8146-5701

Funding

Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Inbal Billie Nahum-Shani · 2021 to 2026
$18.2M
Adaptive intervention strategies to optimize PrEP clinical evaluation and uptake in stimulant-using menR34DA046367 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRICO, ADAM WAYNE, GROV, CHRISTIAN · 2019 to 2021
$707k
NIDA NIH HHS P50 DA054039NIDA NIH HHS R34 DA046367
6 · The paper itself

Abstract

objectiveThis pilot sequential multiple assignment randomized trial estimated the feasibility, acceptability, and scalability of telehealth motivational enhancement interventions for optimizing HIV prevention efforts in sexual minority men (SMM) who use stimulants.

methodSeventy SMM who use stimulants with nonreactive HIV results that were not taking preexposure prophylaxis (PrEP) were randomized to: (a) a two-session motivational interviewing (MI) intervention focusing on PrEP use and concomitant risk behaviors; or (b) a contingency management (CM) intervention with financial incentives for PrEP clinical evaluation ($50) and filling a PrEP prescription ($50). After 3 months, participants who reported they had not filled a prescription for PrEP were randomized a second time to: (a) switch to a second-stage intervention (i.e., MI + CM); or (b) continue with assessments only.

resultsThere was a robust engagement in the interventions, which participants described as flexible and nonjudgmental. Participants reported using CM incentives to meet basic needs and indicated that MI sessions improved their understanding of PrEP. The estimated cost of intervention delivery per participant was $404 for MI, $236 for CM, and $475 for MI + CM. Across both randomizations, participants who received CM only were most likely to provide verified evidence of PrEP use over 6 months, and there were potential benefits for reducing concomitant risk behaviors in nonresponders receiving MI + CM. Prior PrEP use and increases in PrEP intentions were significantly associated with verified PrEP use.

conclusionAlthough more definitive trials are needed to examine effectiveness, telehealth motivational enhancement interventions are promising, scalable approaches for optimizing HIV prevention among SMM who use stimulants. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

Indexed as

HIV InfectionsMotivational InterviewingPre-Exposure ProphylaxisSexual and Gender MinoritiesAdultHomosexuality, MaleHumansMaleMiddle AgedMotivationPilot ProjectsTelemedicineYoung Adult

Identifiers

PMID39992777
PMCPMC11980644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.