Evidence map›Paper›PMID 39992709›Full record

ArticleJournal of the American Chemical Society2025

Leveraging Immunogenic Cell Death to Enhance the Immune Response against Malignant Pleural Mesothelioma Tumors.

Meng Rui Chang, Egor M Matnurov, Chengnan Wu, Jemma Arakelyan, Ho-Jung Choe, Vladimir Kushnarev, Jian Yu Yap, Xiu Xuan Soo, Mun Juinn Chow, Walter Berger and 2 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Three Is Better than One: A Multimetal Complex that Triggers Immunogenic Cell Death.Angewandte Chemie (International ed. in English) · 2025
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Meng Rui ChangDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117543, Singapore.
Egor M MatnurovDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.
Chengnan WuDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.
Jemma ArakelyanDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.
Ho-Jung ChoeDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.
Vladimir KushnarevDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.
Jian Yu YapDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117543, Singapore.
Xiu Xuan SooDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117543, Singapore.
Mun Juinn ChowDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117543, Singapore.
Walter BergerCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8A, Vienna 1090, Austria.ORCID 0000-0003-0014-1658
Wee Han AngDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117543, Singapore.
Maria V BabakDrug Discovery Lab, Department of Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR 999077, People's Republic of China.ORCID 0000-0002-2009-7837

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although various metal-based compounds have exhibited excellent immunogenic cell death (ICD)-inducing properties both

Indexed as

Antineoplastic AgentsCoordination ComplexesImmunogenic Cell DeathLung NeoplasmsMesotheliomaMesothelioma, MalignantPleural NeoplasmsAnimalsCell Line, TumorHumansMicePhagocytosisAntineoplastic AgentsCoordination Complexes

Identifiers

PMID39992709
PMCPMC11887451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.