Evidence map›Paper›PMID 39992401›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Development of [

Xuejun Wen, Tianzhi Zhao, Hongzhang Yang, Mengqi Shi, Xin Jie Wee, Jiayu Fu, Min Lin, Zhenyue Zhang, Maosheng Zou, David Green and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Deciphering the Tumor Uptake of Heterobivalent (SSTJournal of medicinal chemistry · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xuejun Wen *Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore.
Tianzhi Zhao *Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore.
Hongzhang YangDepartment of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore.
Mengqi ShiDepartment of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore.
Xin Jie WeeClinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore.
Jiayu FuYantai Lannacheng Biotechnology Co., Ltd., Yantai, 264100, China.
Min LinYantai Lannacheng Biotechnology Co., Ltd., Yantai, 264100, China.
Zhenyue ZhangYantai Lannacheng Biotechnology Co., Ltd., Yantai, 264100, China.
Maosheng ZouYantai Lannacheng Biotechnology Co., Ltd., Yantai, 264100, China.
David GreenClinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore.
Xiaoming WuYantai Lannacheng Biotechnology Co., Ltd., Yantai, 264100, China. xmwu@dcb-group.com.
Xiaoyuan ChenDepartment of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore. chen.shawn@nus.edu.sg.ORCID 0000-0002-9622-0870
Jingjing ZhangDepartment of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119074, Singapore. j.zhang@nus.edu.sg.

Funding

National University of Singapore NUHSRO/2020/133/Startup/08
6 · The paper itself

Abstract

purposeProstate-specific membrane antigen (PSMA) radioligand therapy (PRLT) has become a promising option for treating metastatic castration-resistant prostate cancer (mCRPC). Radioligands labelled with the

methodsLNC1011 (Dan-PSMA) was synthesised based on a PSMA-binding ligand with the addition of a dansylated amino acid. Systematic radiochemical analyses were conducted to confirm the successful synthesis and radiolabelling of [

results[

conclusion[

Indexed as

ActiniumAlpha ParticlesProstatic NeoplasmsRadiopharmaceuticalsAnimalsCell Line, TumorGlutamate Carboxypeptidase IIHumansMaleMiceTissue DistributionActiniumActinium-225Glutamate Carboxypeptidase IIRadiopharmaceuticals225AcLNC1011Prostate cancerPSMATargeted alpha therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.