Evidence map›Paper›PMID 39992384›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2025

Association between diabetes and heart failure after coronary artery bypass grafting: Danish register-based cohort study.

Benedicte Bay Oxholm Brodersen, Line Tribler Kristiansen, Sidsel le Fevre Karlsen, Jeppe Hauch, Jan Jesper Andreasen, Kristian H Kragholm, Maria Lukács Krogager, Lars Valeur Køber, Peter Christian Leutscher, Dorte Melgaard and 5 more

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Benedicte Bay Oxholm BrodersenThe Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Line Tribler KristiansenThe Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Sidsel le Fevre KarlsenThe Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Jeppe HauchThe Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Jan Jesper AndreasenDepartment of Cardiothoracic Surgery, Aalborg University Hospital, Aalborg, Denmark.
Kristian H KragholmDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Maria Lukács KrogagerDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Lars Valeur KøberDepartment of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Peter Christian LeutscherCenter for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark.
Dorte MelgaardDepartment of Clinical Medicine, Copenhagen University, Copenhagen, Denmark.
Nisha I ParikhDepartment of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA, USA.
Morten SchouDepartment of Cardiology, Herlev and Gentofte Hospital, Copenhagen, Denmark.
Peter SøgaardDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
Christian Torp-PedersenDepartment of Cardiology, Nordsjællands Hospital, Copenhagen, Denmark.
Marc Meller SøndergaardDepartment of Cardiology, Aalborg University Hospital, Aalborg, Denmark. KJ01IH@dcm.aau.dk.ORCID http://orcid.org/0000-0001-6059-4478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIschemic heart disease (IHD) is the leading cause of mortality in the world with an increasing incidence. One of the interventions to treat IHD is coronary artery bypass grafting (CABG) and people with diabetes mellitus (DM) account for approximately one quarter of all patients who undergo coronary revascularization. Furthermore, people with DM have a higher risk of mortality due to heart failure (HF).

objectiveWe aim to describe the risk of developing HF after CABG in patients with versus without DM.

methodsThrough a large nationwide register-based cohort study, patients who underwent CABG from January 1, 2000 to December 31, 2020 were included. In addition to Cox regression, g-formula methods based on multivariable Cox regression were performed to estimate the absolute risk (AR) and risk difference (RD) of the association between DM status and HF outcome, and between DM status and mortality.

resultsA total of 34,855 patients were included in this study, consisting of 6909 (19.8%) DM patients. The AR of HF after CABG in the 10th year was 35.1% versus 26.4% for patients with versus without DM (p < 0.001), respectively. The RD of HF for each exceeding year (3.7 percentage point (pp.) in the 1st year versus 8.6 pp. in the 10th year) was higher for patients with DM compared to those without DM.

conclusionThe risk of HF was significantly higher up to ten years after CABG in patients with DM compared to those without DM.

Indexed as

Coronary Artery BypassCoronary Artery DiseaseDiabetes MellitusHeart FailureMyocardial IschemiaPostoperative ComplicationsRegistriesAgedCohort StudiesDenmarkFemaleHumansIncidenceMaleMiddle AgedRisk AssessmentCoronary artery bypass graftingDiabetes mellitusHeart failureMortality

Identifiers

PMID39992384
PMCPMC12058951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.