ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
The mediating effect of positive coping in the association between inner strength and demoralization in lung cancer chemotherapy patients.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A Mobile-Based Mindfulness Intervention for Reducing Demoralization in Patients on Maintenance Hemodialysis: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- The Mediating Role of Inner Strength in the Relationship Between Illness Perception and Self-Management in Older Adults with Advanced Lung Cancer: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Maternal Inner Strength Mediates the Longitudinal Association Between Family Emotional Expression and Fear of Childbirth: A Cross-Lagged Panel Mediation Analysis.International journal of women's health · 2026Article
- Application Efficacy of Nursing Interventions Guided by the Medication-Psychological-Nursing-Family-Support (MPNFS) Framework in Mitigating Cancer-Related Fatigue and Enhancing Pulmonary Function Among Lung Cancer Patients Undergoing Chemotherapy.Cancer management and research · 2025Article
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Authors and funding
7 authors.
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Abstract
purposeTo determine the influence of inner strength on demoralization in patients receiving chemotherapy for lung cancer and confirm the mediating role of positive coping style.
methodsThis study was a cross-sectional study and included 210 patients from three general hospitals in China. A sociodemographic questionnaire, Inner Strength Scale, Simplified coping style subscale, and Demoralization Scale-II were applied. A structural equation model was conducted to estimate the hypothesis model of demoralization and explore the potential mediating mechanism.
resultsInner strength was positively correlated with positive coping style (P < 0.01). Inner strength, positive coping style, and demoralization were negatively correlated (P < 0.01). Furthermore, positive coping style mediated the relationship between inner strength and demoralization (β = - 0.269 (95% CI, - 0.415, - 0.159), P < 0.01), accounting for 37.41% of the total effect.
conclusionThe results suggest a negative association between inner strength and demoralization in patients with lung cancer undergoing chemotherapy. Positive coping style as a mediating variable provided the impetus for the demoralization. Healthcare professionals might enhance the inner strength of lung cancer patients undergoing chemotherapy by carrying out targeted interventions and encouraging them to adopt positive coping strategies, which can reduce the level of demoralization and promote mental health.
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