Evidence map›Paper›PMID 39992123›Full record

ArticleApplied and environmental microbiology2025

Eco-microbiology: discovering biochemical enhancers of PET biodegradation by

Felipe-Andrés Piedra, Miguel A Salazar, Sara Abouelniaj, Raayed Rahman, Justin C Clark, Yimo Han, Zhao Wang, Anthony Maresso

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felipe-Andrés PiedraDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-0100-2919
Miguel A SalazarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Sara AbouelniajDepartment of Materials Science and NanoEngineering, Rice University, Houston, Texas, USA.
Raayed RahmanDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Justin C ClarkDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Yimo HanDepartment of Materials Science and NanoEngineering, Rice University, Houston, Texas, USA.
Zhao WangDepartment of Materials Science and NanoEngineering, Rice University, Houston, Texas, USA.ORCID 0000-0003-4897-9986
Anthony MaressoDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.

Funding

Molecular Assembly of Bacterial Tripartite Multidrug Efflux PumpsR01AI179879 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI Zhao Wang · 2024 to 2026
$1.9M
NIAID NIH HHS R01 AI179879
6 · The paper itself

Abstract

The scale of plastic pollution boggles the mind. Nearly 400 megatons of virgin plastics are produced annually, with an environmental release rate of 80%, and plastic waste, including microplastics and nanoplastics, is associated with a plethora of problems. The naturally evolved abilities of plastic-degrading microbes offer a starting point for generating sustainable and eco-centric solutions to plastic pollution-a field of endeavor we term eco-microbiology. Here, we developed an iterative discovery procedure coupling faster polyethylene terephthalate (PET)-dependent bioactivity screens with longer-term PET biodegradation assays to find biochemical boosters of PET consumption by the bacterium IMPORTANCE: Plastic pollution is an urgent issue. Adding to the well-known problems of bulk plastic litter, shed microplastics and nanoplastics are globally distributed, found in diverse organisms including human foodstuffs and tissues, and increasingly associated with chronic disease. Solutions are needed and the microbial world offers abundant help via naturally evolved consumers of plastic waste. We are working to accelerate polyethylene terephthalate (PET) plastic biodegradation by

Indexed as

BurkholderialesPolyethylene TerephthalatesBiodegradation, EnvironmentalPolyethylene Terephthalatesbiodegradationbioremediationeco-microbiologyenvironmental microbiologyextrinsic biochemical stimulationfermentationPETPiscinibacter sakaiensisplastic pollution

Identifiers

PMID39992123
PMCPMC11921318

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.