ArticlePhysics and imaging in radiation oncology2025
Accuracy-dependent dose-constraints and dose-based safety margins for organs-at-risk in radiotherapy.
Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Updating historical normal tissue dose/volume constraints to current levels of treatment precision and accuracy.Physics and imaging in radiation oncology · 2025Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background and purpose: Geometrical uncertainties in radiotherapy are generally accounted for by margins for tumors, but their effect on organs-at-risk (OARs) is often ignored. We developed a model that incorporates dose- and geometry-based uncertainties in OAR planning using dose constraints. Materials and methods: Radiotherapy uncertainties cause real dose-volume histograms (DVHs) to spread around the planned DVH. With a Results: Results varied per OAR, fractionation, and constraint-type. If our 2.5mm/3% MD Conclusions: We introduced a first model relating dose constraints and complication probabilities with treatment uncertainties and safety margins for OARs. Among other things, it quantified how higher constraints can be applied with increasing radiotherapy accuracy.
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