Evidence map›Paper›PMID 39991769›Full record

ArticleInternational journal of medical sciences2025

S1R mediates NRF2 dependent ferroptosis of renal tubular epithelial cells to promote renal fibrosis in diabetic nephropathy.

Cheng Yuan, Fengpei Chang, Qiuyuan Zhou, Feng Chen, Xueyun Gao, Ayinigaer Yusufu, Jinhu Chen, Zejin Liao, Xiaoyan Wu, Lihua Ni

Abstract read
In one paragraph

Article in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cheng YuanDepartment of Oncology, Yichang Central People's Hospital and The First College of Clinical Medical Science, China Three Gorges University Yichang, Hubei, China.
Fengpei ChangDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Qiuyuan ZhouDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Feng ChenDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Xueyun GaoDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Ayinigaer YusufuDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Jinhu ChenDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Zejin LiaoDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Xiaoyan WuDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Lihua NiDepartment of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetic NephropathiesFerroptosisNF-E2-Related Factor 2Receptors, sigmaAnimalsCell LineDisease Models, AnimalEpithelial CellsFibrosisHumansKidney TubulesMaleMiceSigma-1 ReceptorSignal TransductionNFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2Receptors, sigmaSigma-1 ReceptorDiabetic nephropathyferroptosisnuclear factor erythroid 2-related factor 2 (NRF2)renal fibrosissigma-1 receptor (S1R)

Identifiers

PMID39991769
PMCPMC11843141

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.