ArticleFrontiers in public health2025
Impact of healthcare-associated infections on in-hospital outcomes during the COVID-19 era: a multicenter comparative study of 20,942 isolated microorganisms from ICU patients.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antibiotic resistance and bacterial co-infections in COVID-19 patients in Iran: a systematic review and meta-analysis of hospitalized and non-hospitalized cases.BMC infectious diseases · 2025Pooled it
- Prevalence and Determinants of Hospital-Acquired Infections in Intensive Care Units Before and After the COVID-19 Pandemic: A Retrospective Descriptive Surveillance Study at a Tertiary Care Hospital in Iran.Health science reports · 2026Article
- Clinical Outcomes and Risk Factors of Healthcare-Associated Infections in Surgical Wards: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Multidrug-resistant uropathogens in pediatric urinary tract infections: a multicenter retrospective trend analysis (2020-2024).Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Epidemiology of Healthcare-Associated Infections Caused by Multidrug-Resistant Bacteria and Antimicrobial Resistance Patterns in a Romanian Tertiary Care Hospital.Journal of clinical medicine · 2026Article
- Burden of antimicrobial resistance and estimated economic impact ofNew microbes and new infections · 2025Article
- Burden of Healthcare-Associated Infections on Mortality Among COVID-19 Hospitalized Patients.Journal of clinical medicine · 2025Article
- Burden of inflammatory enteritis caused by diarrheagenicPreventive medicine reports · 2025Article
- Analysis of ICU resistome dynamics in patients, staff and environment for the identification of predictive biomarkers of sepsis and early mortality.Scientific reports · 2025Article
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5 authors.
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Abstract
Background: Healthcare-associate infection (HAI) has been one of the health care issues worldwide. During the COVID-19 pandemic, HAI prevention was considered a vital aspect of the clinical management of COVID-19. In the present study, we aimed to compare the frequency of HAIs in ICU-admitted cases within and before the COVID-19 era. Methods: This multicenter retrospective study applied a descriptive-analytical approach to investigate the frequency of HAIs in the ICU departments of hospitals affiliated with Tehran University of Medical Sciences from 2017 to 2022. Results: Overall, 14,268 cases with 20,942 isolated microorganisms were recruited for this study, with 8,289 (58.1%) of them being male and 5,975 (41.9%) being female. A total of 6,722 (47.1%) cases with 9,917 (47.4%) isolated microorganisms were documented in the pre-COVID-19 era, while 7,546 (52.9%) patients with 11,025 (52.64%) were reported in COVID-19 era. Of 14,268 patients admitted to the ICU during the study period, 9,197 (64.8%) were discharged and 5,071 died (35.5%), of which 1,970 (29.3%) occurred in pre-COVID and 4,752 (70.7%) in the COVID-19 era ( Conclusion: COVID-19 changed the pattern of HAIs and also increased their mortality. Overall, the findings of this study emphasize the importance of continuous monitoring and improvement of infection control measures in ICUs to reduce the incidence of HAIs and improve patient outcomes.
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