Evidence map›Paper›PMID 39991496›Full record

ArticleSurgical case reports2025

Improvement of Oral Intake after Treatment Using Enteral Feeding Tube for Large Advanced Gastric Cancer Invading Proximal Stomach: A Case Series of 20 Patients.

Koichi Hayano, Yoshihiro Kurata, Yasunori Matsumoto, Ryota Otsuka, Nobufumi Sekino, Takeshi Toyozumi, Akira Nakano, Tadashi Shiraishi, Masaya Uesato, Gaku Ohira and 1 more

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Koichi HayanoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Yoshihiro KurataDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Yasunori MatsumotoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Ryota OtsukaDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Nobufumi SekinoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Takeshi ToyozumiDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Akira NakanoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Tadashi ShiraishiDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Masaya UesatoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Gaku OhiraDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Hisahiro MatsubaraDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with large Stage IV gastric cancer (GC) invading the proximal stomach find it difficult to receive not only bypass surgery but also S-1-based chemotherapy. This study aimed to show our treatment results for those GC patients using elementary diet (ED) tubes, which enabled S-1-based chemotherapy and nutrition support. CASE PRESENTATION: We evaluated 20 patients (13 men and 7 women; median age 70 years) with large Stage IV GCs (8.7-21.9 cm) invading the proximal stomach, who were admitted due to inability to eat, treated with S-1-based chemotherapy using an ED tube. The duration from the initiation of the chemotherapy to the improvement of oral intake, changes in nutritional status, and disease-specific survival (DSS) were retrospectively investigated. Two of the 20 patients failed to complete even one cycle of chemotherapy due to severe nausea or diarrhea. The other 18 patients improved oral liquid intake after 47.5 ± 18.8 days, and 17 patients improved oral solid food intake after 54.5 ± 19.6 days from the start of chemotherapy. In addition, three patients (16.7%) could receive conversion surgery after improvement of oral intake. The median DSS of those 18 patients was 13.1 months. Serum albumin level and prognostic nutritional index (PNI) were significantly improved after about 1 month of the treatment (both

conclusionsGiven a high oral intake success rate, S-1-based chemotherapy using an ED tube can be a promising treatment option for large Stage IV GC with poor oral intake.

Indexed as

enteral feeding tubeenteral nutritiongastric cancerS-1

Identifiers

PMID39991496
PMCPMC11842876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.