Evidence map›Paper›PMID 39991425›Full record

ArticleCureus2025

Comparative Effect of Individual Herbs and Their Combination on Sucrose Tolerance in Normoglycemic Rats and Assessment of Sensory and Nutritional Attributes of Fortified Bread With Polyherbal Formulation.

Fauzia Bano, Seema Kanojia, Arvind K Srivastava

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fauzia BanoDepartment of Food and Nutrition, Era University, Lucknow, IND.
Seema KanojiaDepartment of Food and Nutrition, Era University, Lucknow, IND.
Arvind K SrivastavaDepartment of Food and Nutrition, Era University, Lucknow, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionType 2 diabetes mellitus (T2DM) is a substantial worldwide health issue characterized by chronic hyperglycemia and secondary health complications. The current investigation intends to assess the in vivo hypoglycemic potential of selected medicinal herbs ( METHODOLOGY: Male Wistar albino rats have been allocated into standard and experimental groups, receiving individual herb crude powder and PHF at different doses, i.e., 25, 50, 75, and 100 mg/kg of dose on post-oral sucrose-loaded (5 mg/kg of body weight) rats. The blood glucose levels have been assessed every 0, 30, 60, 90, and 120 minutes. The area under the curve (AUC) was determined. Both sensory and proximate evaluations were performed on the bread.

resultThe results demonstrated a significant (p<0.05) lowering in the blood glucose levels with 75 and 100 mg/kg of dose at different time intervals in rats treated with PHF in contrast to the control group, while the administration of individual herbs does not illustrate any noteworthy changes in the levels of blood glucose except

conclusionThe combination of herbs showed a synergistic effect, leading to enhanced glucose regulation in an oral sucrose-loaded rat model, and PHF at 75 and 100 mg/kg of dose possess better hypoglycemic activity as compared to individual herbs. The utilization of PHF in dietary products may be recommended as a nutraceutical product for the mitigation of T2DM.

Indexed as

diabetes mellitusfortificationpolyherbal formulationsensory attributessynergistic effect

Identifiers

PMID39991425
PMCPMC11846129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.