ArticleCureus2025
Hemorrhagic Pericardial Effusion and Cardiac Tamponade in B-chronic Lymphocytic Leukemia Treated With Ibrutinib: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are few reports of non-malignant hemorrhagic pericardial effusion and cardiac tamponade in patients with B-chronic lymphocytic leukemia (B-CLL) who were not concurrently treated with an anticoagulant or an anti-platelet agent. We report the case of a 57-year-old woman with B-CLL treated for 54 months with single-agent ibrutinib who developed non-malignant hemorrhagic pericardial effusion and cardiac tamponade. She recovered after pericardiocentesis and the discontinuation of ibrutinib treatment. We conclude that the pathogenesis of her hemorrhagic pericardial effusion involved a combination of abnormal coagulation and platelet dysfunction typical of B-CLL, off-target kinase effects of ibrutinib on platelets, and serosal inflammation.
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