Evidence map›Paper›PMID 39991189›Full record

ArticleAperture neuro2023

Evaluating the capabilities and challenges of layer-fMRI VASO at 3T.

Laurentius Renzo Huber, Lisa Kronbichler, Rüdiger Stirnberg, Philipp Ehses, Tony Stöcker, Sara Fernández-Cabello, Benedikt A Poser, Martin Kronbichler

Abstract read
In one paragraph

Article in Aperture neuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. NORDIC denoising on VASO data.Frontiers in neuroscience · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laurentius Renzo HuberMBIC, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Lisa KronbichlerDepartment of Psychiatry, Psychotherapy and Psychosomatics, Christian-Doppler Medical Centre, PMU, Salzburg, Austria.
Rüdiger StirnbergGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Philipp EhsesGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Tony StöckerGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Sara Fernández-CabelloNorwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, Uni Oslo, Oslo, Norway.
Benedikt A PoserMBIC, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Martin KronbichlerNeuroscience Institute, Christian Doppler Medical Centre, PMU, Salzburg, Austria.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Intramural NIH HHS Z99 MH999999NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Sub-millimeter functional imaging has the potential to capture cortical layer-specific functional information flow within and across brain systems. Recent sequence advancements of fMRI signal readout and contrast generations resulted in wide adaptation of layer-fMRI protocols across the global ultra-high-field (UHF) neuroimaging community. However, most layer-fMRI applications are confined to one of ≈100 privileged UHF imaging centers, and sequence contrasts with unwanted sensitivity to large draining veins. In this work, we propose the application of vein-signal free vascular space occupancy (VASO) layer-fMRI sequences at widely accessible 3T scanners. Specifically, we implement, characterize, and apply a cerebral blood volume (CBV)-sensitive VASO fMRI at a 3T scanner setup, as it is typically used in the majority of cognitive neuroscience and clinical neuroscience fMRI studies. We find that the longer

Indexed as

3 TeslaCBVcortical depth-dependent fMRIlaminar fMRIlayer-fMRIsub-millimeter fMRIVASO

Identifiers

PMID39991189
PMCPMC11845223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.