Trial reportClinical interventions in aging2025
Effect of Exercise and Nutrition Intervention for Older Adults with Impaired Physical Function with Preserved Muscle Mass (Functional Sarcopenia): A Randomized Controlled Trial.
Trial report in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative effectiveness of protein or protein-related supplementation combined with resistance or functional exercise for sarcopenia in older adults: a systematic review and network meta-analysis.Frontiers in nutrition · 2026Pooled it
- Effects of nutritional guidance on frailty in older adults: A systematic review.The journal of nutrition, health & aging · 2026Pooled it
- Exercise and Nutrition for Sarcopenia: A Systematic Review and Meta-Analysis with Subgroup Analysis by Population Characteristics.Nutrients · 2025Pooled it
- Combined Psychoeducational and Exercise Training Intervention to Improve Mental Health and Physical Functioning in Late-Life: A Randomized Controlled Trial.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Trial
- Review
- Sarcopenia and Walking Recovery in Older Adults: A Mini-Review of Evidence and Rehabilitation Implications.Journal of clinical medicine · 2026Review
- Differential Effects of Stroke Stage and Age on Sarcopenia in Stroke Patients: A Cross-Sectional Study.Life (Basel, Switzerland) · 2026Article
- Advances in Clinical Management Strategies for Sarcopenia: From Exercise and Nutrition to Pharmacotherapy and Comprehensive Interventions.Molecular neurobiology · 2026Review
- Review
- Sarcopenia: From Global Consensus to Korean Implementation - A Narrative Review and Standpoint.Annals of geriatric medicine and research · 2026Review
- Protocol for a Pilot Two-Arm Crossover Randomized Controlled Trial of the ACTIVE Intervention for Older Adults with and Without Mild Dementia and Their Care Partners.Journal of clinical medicine · 2026Article
- Declines in Activities in Daily Living of Older Adults with Sarcopenia Were Associated with Gait Speed.Medicina (Kaunas, Lithuania) · 2026Article
- Muscle mass and function in patients with type 2 diabetes mellitus: a characteristic analysis based on sex, age, and BMI.Frontiers in endocrinology · 2026Article
- The Impact of Nutritional Supplements on Sarcopenia: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Nutrition and exercise for sarcopenia treatment.Osteoporosis and sarcopenia · 2025Review
- Effect of a multicomponent intervention on institutionalization-free survival in older adults with sarcopenia: aFrontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Functional sarcopenia is characterized by decreased physical performance and grip strength despite preserved muscle mass. The effectiveness of a program combining exercise and nutritional support-known interventions for individuals with low muscle mass-was evaluated for its impact on older adults with functional sarcopenia. Methods: An unblinded, parallel-group randomized controlled trial was conducted in a public medical center in a rural Korean community. Eligible older adults with functional sarcopenia were randomized into either the intervention group, receiving a 12-week program of group exercises and nutritional support, or the control group, receiving education on lifestyle management. Outcomes measured included changes in gait speed, grip strength, physical performance, and quality of life indices. Results: The study enrolled 42 participants, with 21 allocated to each group. Compared with the control group, the intervention group showed significant improvements in the primary outcome of gait speed (mean change (m/s) 0.24 vs 0.00, p<0.001) and secondary outcomes, such as Short Physical Performance Battery scores, grip strength, and quality of life. No significant adverse events were reported. Conclusion: The 12-week exercise and nutritional intervention significantly enhanced physical performance, grip strength, and quality of life among community-dwelling older adults with functional sarcopenia. This suggests that strategies commonly recommended for sarcopenia, including exercise and nutritional support, are also beneficial for individuals with functional sarcopenia, indicating the potential for broader application of such interventions.
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