Evidence map›Paper›PMID 39990857›Full record

ArticleAdvanced functional materials2024

Wireless Peristaltic Pump for Transporting Viscous Fluids and Solid Cargos in Confined Spaces.

Saksham Sharma, Laura Caroline Jung, Nicholas Lee, Yusheng Wang, Ane Kirk-Jadric, Rishi Naik, Xiaoguang Dong

Abstract read
In one paragraph

Article in Advanced functional materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saksham SharmaDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA.
Laura Caroline JungDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA.
Nicholas LeeDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA.
Yusheng WangDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA; Vanderbilt Institute for Surgery and Engineering, Vanderbilt University, Nashville, TN 37212, USA.
Ane Kirk-JadricDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA.
Rishi NaikVanderbilt School of Medicine, Vanderbilt University, Nashville, TN 37240, USA.
Xiaoguang DongDepartment of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, USA; Vanderbilt Institute for Surgery and Engineering, Vanderbilt University, Nashville, TN 37212, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37212, USA; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN 37212, USA.

Funding

Wirelessly Actuated Ciliary Stent for Minimally Invasive Treatment of Cilia DysfunctionR21EB035200 · NIBIB · VANDERBILT UNIVERSITY · PI Xiaoguang Dong · 2024 to 2026
$617k
NIBIB NIH HHS R21 EB035200
6 · The paper itself

Abstract

The transport of fluids and solids is a vital process inside the human body, facilitated by the wave-like motion in the lumen called peristalsis. However, peristalsis may be compromised due to tumor growth, resulting in difficulties in lumen motility. The dysmotility of the human lumen can result in blockages and pose numerous challenges, including aspiration in the lungs and reproductive issues in the female oviduct. Restoring peristalsis in medical devices, such as medical stents, can prevent device blockage and promote effective transport. Here, a wirelessly actuated soft robotic undulating pump designed to efficiently transport both viscous fluidic and solid cargos is proposed. The kinematics of the single sheet and the coordination between pairs are systematically designed to generate undulation and peristalsis, enabling the pumping of both liquids and solids. The integration of the undulating pump is demonstrated onto an esophageal stent. The same undulating motion-based pumping mechanism can be adapted for usage in other organs, such as the female oviduct, thereby offering potential applications for treating lumen dysmotility in various diseases. The proposed wirelessly actuated robotic pumping mechanism holds promise in facilitating diverse implantable medical devices aimed at treating diseases characterized by impaired peristalsis and dysmotility.

Indexed as

esophageal stentmagnetic actuationperistaltic pumpsoft robot

Identifiers

PMID39990857
PMCPMC11845220

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.