Evidence map›Paper›PMID 39990854›Full record

ReviewSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2024

[Research Progress in Imaging Investigation of TERT Promoter Mutations in Gliomas].

Yujue Zhong, Xiaoxiao Ma, Qi Duan, Haoxuan Lu, Jinhao Lyu, Xin Lou

Abstract readReviewEnglish Abstract
In one paragraph

Review in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Study of the Correlation Between MRI Parameters, Microvascular Density, and Prognosis in Glioma].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yujue Zhong( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.
Xiaoxiao Ma( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.
Qi Duan( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.
Haoxuan Lu( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.
Jinhao Lyu( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.
Xin Lou( 100853) Department of Diagnostic Radiology, The First Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatic mutations in the promoter region of telomerase reverse transcriptase (TERT), a critical mechanism for telomerase reactivation, play a key role in tumorigenesis. The status of TERT promoter mutation serves as a crucial molecular biomarker for glioma assessment and classification, and is essential for early diagnosis of glioma subtypes, guiding treatment decision-making, and improving patient prognosis. With the recognition of the importance of molecular subtyping of gliomas, there has been a surge in research on non-invasive prediction of key molecular biomarkers based on preoperative imaging of gliomas, with a particular focus on TERT promoter studies using radiomics approaches. This article presents a comprehensive review of research on TERT promoter mutations in gliomas and imaging-related studies, with the goal of providing insights for future studies on non-invasive prediction of TERT promoters status and offering important references for the precision diagnosis and treatment of glioma patients.

Indexed as

Brain NeoplasmsGliomaMutationPromoter Regions, GeneticTelomeraseBiomarkers, TumorHumansBiomarkers, TumorTelomeraseTERT protein, humanGliomaMagnetic resonance imagingPositron emission tomographyReviewTelomerase reverse transcriptase

Identifiers

PMID39990854
PMCPMC11839370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.