Evidence map›Paper›PMID 39990761›Full record

ReviewMethodist DeBakey cardiovascular journal2025

Medical Management of Obesity: Current Trends and Future Perspectives.

Andres Calderon Valladares, Maria Aguilera Astudillo, Alexsandra Rojas Drinnon, Samaneh Dowlatshahi, Abhishek Kansara, Jawairia Shakil, Bhargavi Patham

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dietary Supplementation withAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andres Calderon ValladaresHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0009-0006-8514-9067
Maria Aguilera AstudilloHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0009-0001-7124-0656
Alexsandra Rojas DrinnonHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0000-0002-8870-7275
Samaneh DowlatshahiHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0009-0007-4038-7405
Abhishek KansaraHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0000-0002-3686-1035
Jawairia ShakilHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0000-0003-3374-1174
Bhargavi PathamHouston Methodist Hospital, Houston, Texas, US.ORCID https://orcid.org/0000-0002-7052-6310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and overweight have become increasingly significant conditions, affecting more than 70% of the adult population in the United States. These conditions are caused by a combination of factors, including genetic, behavioral, environmental, and medical influences. Obesity is a major risk factor for cardiovascular and metabolic diseases. A comprehensive treatment plan for individuals with obesity must recognize the chronic nature of the condition and offer strategies for weight reduction and long-term cardiometabolic benefits. Over the past several decades, multiple therapeutic options have been implemented to address weight loss, appetite regulation, and caloric expenditure, with the goal of reducing the burden of obesity and improving cardiovascular outcomes. Pharmacological treatment of obesity has focused primarily on the central regulation of appetite and food intake behavior. The introduction of incretin agonists for obesity treatment has ushered in a new era of cardiometabolic health, with a multitargeted mechanism that achieves weight loss, glycemic control, decreased cardiovascular mortality, and other metabolic benefits. This review explores the current pharmacological options and the future of obesity treatment.

Indexed as

Anti-Obesity AgentsCardiovascular DiseasesObesityWeight LossEnergy MetabolismHumansRisk FactorsRisk Reduction BehaviorTreatment OutcomeAnti-Obesity Agentscardiovascular diseaseGLP-1obesitypharmacotherapy

Identifiers

PMID39990761
PMCPMC11844017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.