Evidence map›Paper›PMID 39990742›Full record

ArticleMaterials today. Bio2025

Biointegration of soft tissue-inspired hydrogels on the chorioallantoic membrane: An experimental characterization.

Manuel P Kainz, Mathias Polz, Daniel Ziesel, Marta Nowakowska, Muammer Üçal, Sabine Kienesberger, Sophie Hasiba-Pappas, Raimund Winter, Nassim Ghaffari Tabrizi-Wizsy, Sarah Kager and 5 more

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In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Manuel P KainzInstitute of Biomechanics, Graz University of Technology, Austria.
Mathias PolzInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Daniel ZieselInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Marta NowakowskaDepartment of Neurosurgery, Medical University of Graz, Austria.
Muammer ÜçalDepartment of Neurosurgery, Medical University of Graz, Austria.
Sabine KienesbergerBioTechMed-Graz, Austria.
Sophie Hasiba-PappasResearch Unit for Tissue Regeneration, Repair and Reconstruction, Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Austria.
Raimund WinterResearch Unit for Tissue Regeneration, Repair and Reconstruction, Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, Austria.
Nassim Ghaffari Tabrizi-WizsyDivision of Immunology, Research Unit CAM Lab, Otto Loewi Research Center, Medical University of Graz, Austria.
Sarah KagerInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Theresa RienmüllerInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Julia FuchsInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Michele TerzanoInstitute of Biomechanics, Graz University of Technology, Austria.
Christian BaumgartnerInstitute of Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Austria.
Gerhard A HolzapfelInstitute of Biomechanics, Graz University of Technology, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soft scaffold materials for cell cultures grafted onto the chorioallantoic membrane (CAM) provide innovative solutions for creating physiologically relevant environments by mimicking the host tissue. Biocompatible hydrogels represent an ideal medium for such applications, but the relationship between scaffold mechanical properties and reactions at the biological interface remains poorly understood. This study examines the attachment and integration of soft hydrogels on the CAM using an accessible

Indexed as

Biomimetic hydrogelCell migrationChorioallantoic membraneMechanical matchSoft tissueTissue engineering

Identifiers

PMID39990742
PMCPMC11846936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.