Evidence map›Paper›PMID 39990732›Full record

ArticleIn silico pharmacology2025

Molecular modeling of the interactions of compounds of

Amarachi Chike-Ekwughe, Hassan Taiye Abdulameed, Grace I Adebayo-Gege, Abubakar Usman, Emmanuel Joy Omoyungbo, Adeola Adefoluke Ala, Abayomi Emmanuel Adegboyega, Titilayo Omolara Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In silico pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amarachi Chike-EkwugheDepartment of Life Sciences, FacultyofComputingandAppliedSciences, Baze University, Abuja, Nigeria.
Hassan Taiye AbdulameedDepartment of Biochemistry, Kwara State University, Malete, Nigeria.
Grace I Adebayo-GegeDepartment of Human PhysiologyFaculty of Basic Medical SciencesCollege of Medicine and Health Science, Baze University, Abuja, Nigeria.
Abubakar UsmanDepartment of Livestock and Fisheries, National Agricultural Extension and Research Liason Services, Ahmadu Bello University, Zaria, Nigeria.
Emmanuel Joy OmoyungboBioinformatics Unit, Jaris Computational Biology Centre, Jos, Nigeria.
Adeola Adefoluke AlaDepartment of Zoology, Faculty of Science, University of Ibadan, Ibadan, Nigeria.
Abayomi Emmanuel AdegboyegaPurdue University, West Lafayette, IN USA.
Titilayo Omolara JohnsonDepartment of BiochemistryFaculty of Basic Medical ScienceCollege of Health Sciences, University of Jos, Jos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a significant global health burden that affects the majority of people in the world. Nigeria still accounts for the highest percentage of the worldwide malaria burden, with 27% of estimated malaria cases and 31% of estimated deaths due to malaria in 2022. While antimalarial effects have been attributed to some active compounds from medicinal plants, no study has been conducted on

Indexed as

AntimalarialDihydrofolate reductase-thymidylate synthaseIrvinga womboluMolecular dockingMolecular dynamics

Identifiers

PMID39990732
PMCPMC11839966

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.