Evidence map›Paper›PMID 39990710›Full record

ArticleFrontiers in plant science2025

Optimization of extraction and enrichment process of cannabidiol from industrial hemp and evaluation of its bioactivity.

Junkai Wu, Xiaomeng Zhang, Xiaoqing Liu, Zunlai Sheng, Jianping Hu, Feiyan Zhang

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junkai WuSchool of Pharmacy, Quanzhou Medical College, Quanzhou, China.
Xiaomeng ZhangCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Xiaoqing LiuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Zunlai ShengCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Jianping HuSchool of Pharmacy, Quanzhou Medical College, Quanzhou, China.
Feiyan ZhangSchool of Pharmacy, Quanzhou Medical College, Quanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Methods: The extraction parameters for CBD from industrial hemp were optimized using the Box-Behnken design and response surface methodology (RSM). The purification process involved characterizing the penetration and desorption profiles of CBD on HPD-100 resin. The Results: After optimization, the extraction rate of CBD reached 0.26 ± 0.02%. The use of HP-100 resin in the purification process resulted in a significant enrichment of CBD content, which was 4.2 times higher than that of the crude extract, with a recovery rate of 83.13%. The MIC against Conclusion: These findings contribute to the development of CBD for broader applications in various industries, highlighting its potential as a valuable compound in health and wellness sectors.

Indexed as

bioactivity evaluationcannabidiolenrichment processextraction processindustrial hemp

Identifiers

PMID39990710
PMCPMC11842326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.