ArticlebioRxiv : the preprint server for biology2025
Persistent Disruptions in Prefrontal Connectivity Despite Behavioral Rescue by Environmental Enrichment in a Mouse Model of Rett Syndrome.
Sofie Ährlund-Richter, Jonathan Harpe, Giselle Fernandes, Ruby Lam, Mriganka Sur
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors.
Sofie Ährlund-RichterThe Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-7845-7831 Jonathan HarpeThe Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Giselle FernandesThe Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0003-1388-6392 Ruby LamThe Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-3077-3907 Mriganka SurThe Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0003-2442-5671 Funding
MicroRNA mechanisms of Rett SyndromeR01MH085802 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SUR, MRIGANKA · 2010 to 2025
$6.2MNeuron-astrocyte mechanisms of norepinephrine in goal-directed learningR01MH133066 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MRIGANKA SUR · 2023 to 2026
$2.6MTranslational Post-doctoral Training in NeurodevelopmentT32MH112510 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI DAVID C GLAHN, CHARLES Alexander NELSON · 2017 to 2026
$2.6MAstrocyte-Neuron Circuits Underlying Cortical Mechanisms of Learned BehaviorR01NS130361 · NINDS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MRIGANKA SUR · 2022 to 2026
$2.1MDissecting distinct contributions of different Prefrontal subregions on goal-directed visual attentionK99EY035752 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI AEHRLUND RICHTER, SOFIE · 2024 to 2025
$251kNEI NIH HHS K99 EY035752NIMH NIH HHS R01 MH085802NIMH NIH HHS R01 MH133066NIMH NIH HHS T32 MH112510NINDS NIH HHS R01 NS130361
6 · The paper itselfAbstract
Rett Syndrome, a neurodevelopmental disorder caused by loss-of-function mutations in the
Indexed as
Anterior Cingulate CortexAnterograde tracingAnxietyBDNFPrefrontal cortexRett syndrome
Identifiers
PMID39990439
PMCPMC11844379
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